PHETA2 and OCRL

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid, two hybrid)

		PHETA2	OCRL
Description		PH domain containing endocytic trafficking adaptor 2	OCRL inositol polyphosphate-5-phosphatase
Image		No pdb structure
GO Annotations	Cellular Component	Early Endosome Trans-Golgi Network Cytosol Clathrin-coated Vesicle Recycling Endosome	Photoreceptor Outer Segment Nucleus Cytoplasm Lysosome Early Endosome Golgi Stack Golgi-associated Vesicle Trans-Golgi Network Cytosol Plasma Membrane Clathrin-coated Pit Membrane Clathrin-coated Vesicle Phagocytic Vesicle Membrane Early Endosome Membrane
	Molecular Function	Protein Binding Protein Homodimerization Activity	Phosphatidylinositol-4,5-bisphosphate 5-phosphatase Activity Inositol-polyphosphate 5-phosphatase Activity GTPase Activator Activity Protein Binding Small GTPase Binding Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase Activity Phosphatidylinositol Phosphate 4-phosphatase Activity Phosphatidylinositol-3,5-bisphosphate 5-phosphatase Activity Inositol-1,4,5-trisphosphate 5-phosphatase Activity Inositol-1,3,4,5-tetrakisphosphate 5-phosphatase Activity Inositol Phosphate Phosphatase Activity
	Biological Process	Receptor Recycling Endosome Organization Retrograde Transport, Endosome To Golgi	Lipid Metabolic Process Phosphatidylinositol Biosynthetic Process Signal Transduction Phosphatidylinositol-3-phosphate Biosynthetic Process Regulation Of GTPase Activity Inositol Phosphate Metabolic Process Inositol Phosphate Dephosphorylation Phosphatidylinositol Dephosphorylation Cilium Assembly Membrane Organization
Pathways			Synthesis of PIPs at the plasma membrane Synthesis of PIPs at the Golgi membrane Synthesis of IP2, IP, and Ins in the cytosol Synthesis of IP3 and IP4 in the cytosol Golgi Associated Vesicle Biogenesis Clathrin-mediated endocytosis RHOJ GTPase cycle RAC3 GTPase cycle
Drugs
Diseases
GWAS
Interacting Genes		5 interacting genes: CHADL CLVS2 OCRL PHETA1 PLEKHJ1	15 interacting genes: CDC42 CLTC GOLGA5 GRB2 LHX3 PHETA1 PHETA2 RAB14 RAB1A RAB31 RAB5A RAB6A RAB8A RAC1 TYMS
Entrez ID		150368	4952
HPRD ID		17305	02395
Ensembl ID		ENSG00000177096	ENSG00000122126
Uniprot IDs		Q6ICB4	A0A2X0TVZ9 Q01968 Q504W7
PDB IDs			2KIE 2QV2 3QBT 3QIS 4CMN
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?