CSTF2 and CDSN

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CSTF2	CDSN
Description		cleavage stimulation factor subunit 2	corneodesmosin
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm MRNA Cleavage And Polyadenylation Specificity Factor Complex Nuclear Body Cleavage Body	Cornified Envelope Extracellular Region Plasma Membrane Cell-cell Junction Desmosome
	Molecular Function	RNA Binding MRNA Binding Protein Binding	Protein Homodimerization Activity
	Biological Process	MRNA Polyadenylation Pre-mRNA Cleavage Required For Polyadenylation Cellular Response To Nerve Growth Factor Stimulus	Corneocyte Desquamation Cell Adhesion Epidermis Development Keratinocyte Differentiation Skin Morphogenesis Cell-cell Adhesion Negative Regulation Of Cornification
Pathways		tRNA processing in the nucleus mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs	Formation of the cornified envelope
Drugs
Diseases
GWAS			Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Automobile speeding propensity ( 30643258) Blood protein levels ( 28240269) Hematology traits ( 23263863) Hemoglobin levels ( 32327693) Hip circumference adjusted for BMI ( 34021172) HIV-1 control ( 20041166) Inflammatory bowel disease ( 28067908) Malaria ( 31844061) Multiple myeloma ( 23955597) Schizophrenia ( 28991256) Systemic mastocytosis ( 32752121) Takayasu arteritis ( 25604533) Ulcerative colitis ( 28067908) White blood cell count ( 20139978 21738480)
Interacting Genes		48 interacting genes: ABHD11 AKAP8L ANKRD10 APP ATP23 BAG6 CDSN CEACAM6 CEP126 CHD3 CNOT2 CSTF3 CTBP2 DDX1 ECH1 EEF1G ELP1 ERG28 FAM168B FEZ1 HDHD3 HGS IMMT INCA1 KAT5 METTL15 METTL27 MIR19A MIR92A2 POLR2A POU6F2 PPP1R32 PRDM6 RFX6 SPAG8 SS18L1 STH SUB1 SYMPK TFG TLE3 TLE5 TSC1 UBQLN1 UBQLN4 UFSP1 USP54 ZNF341	39 interacting genes: ACE2 ASPH ATXN1L BAG6 BANP CCHCR1 CEP55 CSTF2 CSTF2T CTNNA3 DAXX DESI1 EIF3F ENKD1 EXOC8 FAM9B HGS HPCAL4 ITPRIPL1 KCNIP3 KLK7 LCN2 NCS1 NELFCD PARVG PLVAP PRKAB2 SGTA SGTB SMARCD1 TGM7 TRIM69 TSGA10 UBQLN1 UBQLN2 UBQLN4 UCHL5 VSNL1 ZDHHC17
Entrez ID		1478	1041
HPRD ID		02652	03998
Ensembl ID		ENSG00000101811	ENSG00000204539
Uniprot IDs		B3V096 B4DUD5 E7EWR4 P33240	G8JLG2 Q15517
PDB IDs		1P1T 2J8P 6Q2I 6TZE
Enriched GO Terms of Interacting Partners?
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