ZNF688 and CCDC57

Number of citations of the paper that reports this interaction (PubMedID 26871637)
172

Data Source:
BioGRID (two hybrid)

		ZNF688	CCDC57
Description		zinc finger protein 688	coiled-coil domain containing 57
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cellular_component Nucleus	Cytoplasm Centrosome Centriole Spindle Microtubule Centriolar Satellite
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Molecular_function Protein Binding Metal Ion Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Biological_process	G2/M Transition Of Mitotic Cell Cycle Microtubule Nucleation Centriole Replication Positive Regulation Of Mitotic Cell Cycle Cilium Assembly
Pathways		Generic Transcription Pathway
Drugs
Diseases
GWAS			Blood metabolite levels ( 24816252) Blood urea nitrogen levels ( 31152163) Proteinuria and chronic kidney disease ( 26420894) Refractive error ( 32231278)
Interacting Genes		112 interacting genes: ABI2 ANKRD11 BEND5 BLZF1 BOLA2 BOLA2B C1orf109 CADPS CALCOCO2 CARD9 CATSPER1 CBY2 CCDC102B CCDC136 CCDC33 CCDC57 CCNC CDKN2D CDR2L CEP44 CEP70 CEP72 CIB3 CRX DEF6 EHMT2 FAM90A1 FBXO7 FCHO1 FHL5 GEM GLYCTK GMPPA GOLGA2 GPANK1 GPRASP2 HMBOX1 HNRNPK HOMEZ HOXA1 HSF2BP IGFN1 IHO1 KHDRBS2 KHDRBS3 KIFC3 KRT13 KRT15 KRT31 KRT40 KRTAP10-3 KRTAP10-9 KRTAP12-2 KRTAP4-2 LDOC1 LMO1 LMO2 MAGED1 MDFI MEOX2 MID2 MIPOL1 MKRN3 MYOZ3 NCK2 NEK6 NFU1 NOTCH2NLA OSTF1 PCBD1 PFKFB1 PHF1 PIH1D2 PLSCR1 PNMA1 PNMA2 POLR1C PSMA3 PSMB1 PSTPIP1 RCOR3 REL RFX6 RINT1 RPGRIP1 SCNM1 SMARCB1 SPAG5 SSX2IP TADA2A TCEANC TCF12 TCF4 TCP11 TEKT4 TENT5B TLE5 TMCC2 TMEM219 TNS2 TRAF1 TRAF2 TRAF4 TRIM23 TRIM27 TRIP6 TTC19 USHBP1 WWP2 ZC4H2 ZGPAT ZNF330	148 interacting genes: ABI1 ABI2 ABLIM1 AMOTL2 ANKRD23 AQP1 ARID5A ARL4A AXIN1 BCAR3 BEX2 C19orf44 C2CD6 C4orf45 C9orf24 CBX8 CBY2 CCDC120 CCDC33 CDC20B CEP57L1 CFAP53 COIL CRTC2 CWF19L2 DCLK2 DISC1 DTX2 ECPAS EFHC2 EIF3D EIF4G1 ELOA EMILIN3 ESS2 FAM107A FAM161A FAM161B FAM228A FAM50B FAM90A1 FH FOXD4L1 FTO GFAP GIGYF1 GPBP1 GPKOW GRPEL1 HAUS1 HBA2 HDX IHO1 IKZF3 INCA1 INTS2 JRK KANK2 KIAA0408 KLF1 KLF15 KPRP KRT4 KRT76 KRTAP13-2 KRTAP13-3 LENG1 LINC00526 LZTS1 MAD1L1 MDM1 MFAP1 MT1E MYOZ3 NAB2 NAPRT NCOA5 NELFE NME4 NUMA1 PAK5 PER1 POM121 PPHLN1 PPP1R18 PPP1R32 PRAM1 PRDM6 PROSER3 PRPF18 PRPF31 PRR3 PSMB4 PTCHD3 PTPN7 RAB3IL1 RASD1 RBM48 RDM1 RINT1 RNF6 ROBO3 RUSC1 RXRB SFI1 SH3KBP1 SHISA6 SIRPA SLC25A48 SMG9 SNRNP35 SORBS3 SPRY1 SYT6 TBC1D22B TCP10L TFIP11 TFPT TIMM44 TLE5 TMEM100 TNNI1 TP53BP2 TRIM14 TRIM29 TSEN54 TSGA10IP TSHZ2 TXLNA USP15 USP2 UTP14C VPS52 YJU2 ZBTB4 ZC2HC1C ZFC3H1 ZGPAT ZMAT2 ZNF417 ZNF436 ZNF474 ZNF552 ZNF648 ZNF655 ZNF688 ZNF835 ZSWIM3
Entrez ID		146542	284001
HPRD ID		14070	14150
Ensembl ID		ENSG00000229809	ENSG00000176155
Uniprot IDs		A0A024QZB6 A0A0S2Z633 P0C7X2	A0A590UJT6 Q2TAC2
PDB IDs
Enriched GO Terms of Interacting Partners?
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