PHETA1 and FCHO1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PHETA1	FCHO1
Description		PH domain containing endocytic trafficking adaptor 1	FCH and mu domain containing endocytic adaptor 1
Image			No pdb structure
GO Annotations	Cellular Component	Early Endosome Trans-Golgi Network Cytosol Clathrin-coated Vesicle Recycling Endosome	Nucleoplasm Cytoplasm Cytosol Plasma Membrane Clathrin-coated Pit Clathrin-coated Vesicle
	Molecular Function	Protein Binding Protein Homodimerization Activity	Protein Binding AP-2 Adaptor Complex Binding
	Biological Process	Receptor Recycling Endosome Organization Retrograde Transport, Endosome To Golgi	Clathrin Coat Assembly Clathrin-dependent Endocytosis
Pathways			Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs
Diseases
GWAS			Basophil count ( 32888494) Coronary artery disease ( 29212778) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Monocyte percentage of white cells ( 32888494) Myocardial infarction ( 33532862)
Interacting Genes		15 interacting genes: ABI2 C11orf68 CYSRT1 FCHO1 GRB2 HOXA1 KRTAP1-3 KRTAP13-2 KRTAP6-3 NCK2 OCRL OIP5 PHETA2 PLEKHJ1 SORBS3	52 interacting genes: ACVR1 APP BYSL CCDC13 CSNK2A1 CWF19L2 DAB2 DDX6 DNAJC5 ELOA EPS15 EPS15L1 EXOSC5 FBXL7 GDF15 GRB7 GUCD1 ITSN1 KAT5 KPRP KRTAP10-1 KRTAP10-5 KRTAP13-2 KRTAP13-4 KRTAP15-1 KRTAP4-12 KRTAP6-1 KRTAP6-3 LGALS14 MAB21L3 NCK1 PCGF1 PHETA1 PHLDA2 PICALM PLAC8 PLSCR4 PRPF3 PRPH PTK6 SH2D4A SMURF1 SRPK2 SYTL4 TCEA2 TCEANC TGFB1 TRIM42 TSPAN4 ZBTB16 ZBTB24 ZNF688
Entrez ID		144717	23149
HPRD ID		08127	16887
Ensembl ID		ENSG00000198324	ENSG00000130475
Uniprot IDs		Q8N4B1	A0A0C3SFZ9 B7ZAZ3 O14526
PDB IDs		3QIS
Enriched GO Terms of Interacting Partners?
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