TMEM86A and KCNA1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TMEM86A	KCNA1
Description		transmembrane protein 86A	potassium voltage-gated channel subfamily A member 1
Image		No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	Endoplasmic Reticulum Cytosol Plasma Membrane Integral Component Of Plasma Membrane Voltage-gated Potassium Channel Complex Cell Surface Integral Component Of Membrane Apical Plasma Membrane Cell Junction Dendrite Cytoplasmic Vesicle Paranode Region Of Axon Presynaptic Membrane Neuronal Cell Body Perikaryon Axon Terminus Juxtaparanode Region Of Axon Calyx Of Held Synapse Glutamatergic Synapse Integral Component Of Postsynaptic Membrane Integral Component Of Presynaptic Membrane
	Molecular Function	Protein Binding Alkenylglycerophosphocholine Hydrolase Activity Alkenylglycerophosphoethanolamine Hydrolase Activity	Voltage-gated Potassium Channel Activity Delayed Rectifier Potassium Channel Activity Potassium Channel Activity Protein Binding Potassium Ion Transmembrane Transporter Activity Disordered Domain Specific Binding Voltage-gated Ion Channel Activity Involved In Regulation Of Presynaptic Membrane Potential Voltage-gated Ion Channel Activity Involved In Regulation Of Postsynaptic Membrane Potential
	Biological Process		Startle Response Potassium Ion Transport Regulation Of Muscle Contraction Chemical Synaptic Transmission Neuroblast Proliferation Cell Communication By Electrical Coupling Magnesium Ion Homeostasis Neuronal Action Potential Hippocampus Development Neuronal Signal Transduction Cellular Protein Localization Regulation Of Membrane Potential Neuromuscular Process Detection Of Mechanical Stimulus Involved In Sensory Perception Of Pain Detection Of Mechanical Stimulus Involved In Sensory Perception Of Touch Protein Homooligomerization Regulation Of Postsynaptic Membrane Potential Cellular Response To Magnesium Ion Potassium Ion Transmembrane Transport Regulation Of Presynaptic Membrane Potential Positive Regulation Of Voltage-gated Potassium Channel Activity
Pathways			Voltage gated Potassium channels
Drugs			Enflurane Amitriptyline Isoflurane Methoxyflurane Promethazine Miconazole Desflurane Dalfampridine Tetraethylammonium Amifampridine
Diseases
GWAS		Ovarian reserve ( 22116950)
Interacting Genes		47 interacting genes: AQP2 AQP3 BCL2L13 CD79A CISD2 CNR2 COQ9 CPLX4 CREB3L1 EBP ERGIC3 FAM209A FFAR2 FKBP7 FNDC9 FXYD3 GJB4 GJB5 GJC1 GORAB GPR37L1 HAVCR2 KASH5 KCNA1 LHFPL5 LMNA MS4A2 MUC1 NCAPH2 PDZK1IP1 PGRMC2 PI16 REEP4 RIC3 RNF185 SCN3B SLC10A6 SLC18A1 SLC30A2 SLC35C2 SLC39A2 SSMEM1 THAP4 TIMMDC1 TMEM31 TMPRSS2 TYROBP	18 interacting genes: APOL2 DLG1 DLG4 DOLK FCER1G GPR152 GPR42 IER3IP1 JAGN1 KCNA10 KCNA3 KCNE4 LAG3 MAL NOMO1 SGTA TMEM14B TMEM86A
Entrez ID		144110	3736
HPRD ID		08292	08885
Ensembl ID		ENSG00000151117	ENSG00000111262
Uniprot IDs		Q8N2M4	Q09470
PDB IDs			2AFL
Enriched GO Terms of Interacting Partners?
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