SYT9 and TRPV1

Number of citations of the paper that reports this interaction (PubMedID 15066994)
110

Data Source:
HPRD (in vivo, two hybrid, in vitro)

		SYT9	TRPV1
Description		synaptotagmin 9	transient receptor potential cation channel subfamily V member 1
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Synaptic Vesicle Membrane Secretory Granule Membrane Clathrin-coated Endocytic Vesicle Membrane Dense Core Granule Exocytic Vesicle Hippocampal Mossy Fiber To CA3 Synapse	Mitochondrion Cytosol Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Integral Component Of Membrane Intrinsic Component Of Plasma Membrane Dendritic Spine Membrane Neuronal Cell Body Postsynaptic Membrane
	Molecular Function	SNARE Binding Phosphatidylserine Binding Calcium Ion Binding Protein Binding Calcium-dependent Phospholipid Binding Phosphatidylinositol-4,5-bisphosphate Binding Syntaxin Binding Clathrin Binding Identical Protein Binding	Transmembrane Signaling Receptor Activity Ion Channel Activity Extracellular Ligand-gated Ion Channel Activity Excitatory Extracellular Ligand-gated Ion Channel Activity Voltage-gated Calcium Channel Activity Calcium Channel Activity Protein Binding Calmodulin Binding ATP Binding Calcium-release Channel Activity Chloride Channel Regulator Activity Phosphatidylinositol Binding Identical Protein Binding Metal Ion Binding Phosphoprotein Binding Temperature-gated Ion Channel Activity
	Biological Process	Regulation Of Dopamine Secretion Vesicle-mediated Transport Calcium-ion Regulated Exocytosis Regulation Of Calcium Ion-dependent Exocytosis Positive Regulation Of Calcium Ion-dependent Exocytosis Regulation Of Insulin Secretion Cellular Response To Calcium Ion Calcium-dependent Activation Of Synaptic Vesicle Fusion	Negative Regulation Of Transcription By RNA Polymerase II Fever Generation Microglial Cell Activation Diet Induced Thermogenesis Peptide Secretion Negative Regulation Of Systemic Arterial Blood Pressure Lipid Metabolic Process Cell Surface Receptor Signaling Pathway Chemosensory Behavior Negative Regulation Of Heart Rate Negative Regulation Of Mitochondrial Membrane Potential Glutamate Secretion Cellular Response To Heat Positive Regulation Of Apoptotic Process Response To Peptide Hormone Positive Regulation Of Nitric Oxide Biosynthetic Process Behavioral Response To Pain Sensory Perception Of Mechanical Stimulus Thermoception Detection Of Temperature Stimulus Involved In Thermoception Detection Of Temperature Stimulus Involved In Sensory Perception Of Pain Detection Of Chemical Stimulus Involved In Sensory Perception Of Pain Release Of Sequestered Calcium Ion Into Cytosol Protein Homotetramerization Excitatory Postsynaptic Potential Smooth Muscle Contraction Involved In Micturition Positive Regulation Of Gastric Acid Secretion Calcium Ion Transmembrane Transport Cellular Response To Alkaloid Cellular Response To ATP Cellular Response To Tumor Necrosis Factor Cellular Response To Acidic PH Cellular Response To Temperature Stimulus Negative Regulation Of Establishment Of Blood-brain Barrier Calcium Ion Import Across Plasma Membrane Response To Capsazepine Cellular Response To Nerve Growth Factor Stimulus
Pathways		Neurexins and neuroligins Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis	TRP channels
Drugs			alpha-Linolenic acid Icosapent Aspartame Tramadol Acetaminophen Camphor Ricinoleic Acid Resiniferatoxin Capsaicin Cannabidiol Zucapsaicin Propacetamol Capsicum oleoresin Nonivamide (S)-camphor Medical Cannabis Nabiximols Cannabidivarin
Diseases
GWAS		3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134) Breast cancer and/or colorectal cancer ( 29698419) Cerebrospinal fluid p-tau levels in mild cognitive impairment ( 29274321) Chagas cardiomyopathy in Tripanosoma cruzi seropositivity ( 24324551) Dietary fat liking ( 32516399) Familial lung cancer ( 29924316) Lead levels ( 26025379) Malaria ( 31844061) Phospholipid levels (plasma) ( 22359512) QRS duration in Tripanosoma cruzi seropositivity ( 24324551)
Interacting Genes		10 interacting genes: CSNK1A1 DNAJC5 NRXN1 SNAP25 SYNCRIP TMBIM6 TMEM50A TRPV1 TUBB UPK1B	9 interacting genes: AKAP5 CALM1 EGFR ITCH PRKCE SNAPIN SYT9 TRPV2 TUBD1
Entrez ID		143425	7442
HPRD ID		11618	03648
Ensembl ID		ENSG00000170743	ENSG00000196689
Uniprot IDs		Q86SS6	Q8NER1
PDB IDs			6L93
Enriched GO Terms of Interacting Partners?
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