PARP4 and TUBA3C

		PARP4	TUBA3C
Description		poly(ADP-ribose) polymerase family member 4	tubulin alpha 3c
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Spindle Microtubule Membrane Extracellular Exosome Ribonucleoprotein Complex	Nucleus Cytoplasm Microtubule
	Molecular Function	DNA Binding NAD+ ADP-ribosyltransferase Activity Protein Binding Enzyme Binding Protein ADP-ribosylase Activity	GTPase Activity Structural Constituent Of Cytoskeleton GTP Binding
	Biological Process	DNA Repair Cellular Protein Modification Process Protein ADP-ribosylation Inflammatory Response Cellular Response To DNA Damage Stimulus Cell Death Response To Xenobiotic Stimulus Regulation Of Telomerase Activity Protein Mono-ADP-ribosylation	Microtubule Cytoskeleton Organization Mitotic Cell Cycle
Pathways		Nicotinamide salvaging Maturation of nucleoprotein Maturation of nucleoprotein	Translocation of SLC2A4 (GLUT4) to the plasma membrane Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane Gap junction assembly MHC class II antigen presentation Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand Recruitment of NuMA to mitotic centrosomes Prefoldin mediated transfer of substrate to CCT/TriC Formation of tubulin folding intermediates by CCT/TriC Post-chaperonin tubulin folding pathway Recycling pathway of L1 Recycling pathway of L1 Hedgehog 'off' state Cilium Assembly Intraflagellar transport RHO GTPases activate IQGAPs RHO GTPases Activate Formins COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic COPI-independent Golgi-to-ER retrograde traffic Mitotic Prometaphase The role of GTSE1 in G2/M progression after G2 checkpoint Carboxyterminal post-translational modifications of tubulin Carboxyterminal post-translational modifications of tubulin HCMV Early Events Assembly and cell surface presentation of NMDA receptors Activation of AMPK downstream of NMDARs Aggrephagy Aggrephagy EML4 and NUDC in mitotic spindle formation Sealing of the nuclear envelope (NE) by ESCRT-III Kinesins Translocation of SLC2A4 (GLUT4) to the plasma membrane Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane Gap junction assembly MHC class II antigen presentation Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand Recruitment of NuMA to mitotic centrosomes Prefoldin mediated transfer of substrate to CCT/TriC Formation of tubulin folding intermediates by CCT/TriC Post-chaperonin tubulin folding pathway Recycling pathway of L1 Recycling pathway of L1 Hedgehog 'off' state Cilium Assembly Intraflagellar transport RHO GTPases activate IQGAPs RHO GTPases Activate Formins COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic COPI-independent Golgi-to-ER retrograde traffic Mitotic Prometaphase The role of GTSE1 in G2/M progression after G2 checkpoint Carboxyterminal post-translational modifications of tubulin Carboxyterminal post-translational modifications of tubulin HCMV Early Events Assembly and cell surface presentation of NMDA receptors Activation of AMPK downstream of NMDARs Aggrephagy Aggrephagy EML4 and NUDC in mitotic spindle formation Sealing of the nuclear envelope (NE) by ESCRT-III Kinesins
Drugs
Diseases
GWAS		Idiopathic intracranial hypertension ( 29608535) Obesity-related traits ( 23251661) Sudden cardiac arrest ( 21658281)	Coronary artery aneurysm in Kawasaki disease ( 27171184) Fasting blood insulin (BMI interaction) ( 22581228) Joint mobility (Beighton score) ( 27182965)
Interacting Genes		4 interacting genes: CCT6A MVP SMAD3 TUBA3C	15 interacting genes: DYNLL1 DYNLT1 EIF3FP2 FYN GRM7 MYC NMI PARP4 PFDN5 PXN SIAH1 TUBG1 UBC XPO4 YWHAQ
Entrez ID		143	7278
HPRD ID		09598	03958
Ensembl ID		ENSG00000102699	ENSG00000198033
Uniprot IDs		Q9UKK3	P0DPH7 P0DPH8 Q1ZYQ1
PDB IDs
Enriched GO Terms of Interacting Partners?
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