ADORA3 and MOV10

		ADORA3	MOV10
Description		adenosine A3 receptor	Mov10 RISC complex RNA helicase
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane	P-body Extracellular Space Nucleus Cytosol Cytoplasmic Stress Granule Cytoplasmic Ribonucleoprotein Granule P Granule
	Molecular Function	G Protein-coupled Adenosine Receptor Activity	RNA Binding Protein Binding ATP Binding ATP Hydrolysis Activity 5'-3' RNA Helicase Activity
	Biological Process	G Protein-coupled Adenosine Receptor Signaling Pathway Inflammatory Response Signal Transduction Activation Of Adenylate Cyclase Activity Regulation Of Heart Contraction Negative Regulation Of Cell Population Proliferation Response To Wounding Negative Regulation Of Cell Migration Negative Regulation Of NF-kappaB Transcription Factor Activity	Negative Regulation Of Transposition, RNA-mediated Post-transcriptional Gene Silencing By RNA Gene Silencing By MiRNA MRNA Cleavage Involved In Gene Silencing By MiRNA Defense Response To Virus Positive Regulation Of MRNA Catabolic Process 3'-UTR-mediated MRNA Destabilization Regulation Of Neuron Projection Arborization
Pathways		Adenosine P1 receptors G alpha (i) signalling events	Pre-NOTCH Transcription and Translation Oxidative Stress Induced Senescence Oncogene Induced Senescence Ca2+ pathway TP53 Regulates Metabolic Genes MAPK6/MAPK4 signaling Transcriptional Regulation by VENTX Regulation of RUNX1 Expression and Activity RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function Regulation of PTEN mRNA translation Competing endogenous RNAs (ceRNAs) regulate PTEN translation Transcriptional Regulation by MECP2 Transcriptional Regulation by MECP2 Estrogen-dependent gene expression Regulation of MECP2 expression and activity NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux
Drugs		Caffeine Adenosine Enprofylline Aminophylline Piclidenoson Fostamatinib
Diseases
GWAS		Energy intake ( 30071075) Obesity-related traits ( 23251661)	Blood pressure ( 21909110) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body size at age 10 ( 32376654) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area ( 32963231) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical surface area (visual PC2) ( 32198502) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Diastolic blood pressure ( 27841878 21909115 28739976 27618452 25249183 30487518) Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962) Glaucoma (primary open-angle) ( 33627673) Height ( 31562340) Hip circumference adjusted for BMI ( 25673412) Hypertension ( 21909115 25249183 30487518) Mean arterial pressure ( 30487518) Mean arterial pressure x alcohol consumption interaction (2df test) ( 29912962) Medication use (diuretics) ( 31015401) Platelet count ( 32888494) Plateletcrit ( 32888494) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Systolic blood pressure ( 27841878 21909115 28739976 27618452 25249183 30487518) Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
Interacting Genes		1 interacting genes: MOV10	4 interacting genes: ADORA3 ATP5PB EIF2AK2 TSPAN2
Entrez ID		140	4343
HPRD ID		08984	14732
Ensembl ID		ENSG00000282608	ENSG00000155363
Uniprot IDs		A0A0J9YWR0 H6VQ59 P0DMS8	Q5JR04 Q9HCE1
PDB IDs		1OEA 1R7N
Enriched GO Terms of Interacting Partners?
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