CORT and SSTR4

Number of citations of the paper that reports this interaction (PubMedID 9205124)
12

Data Source:
BioGRID (unspecified method)
HPRD (in vivo)

		CORT	SSTR4
Description		cortistatin	somatostatin receptor 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Fanconi Anaemia Nuclear Complex Synapse FANCM-MHF Complex	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Neuron Projection
	Molecular Function	G Protein-coupled Receptor Binding Chromatin Binding Neuropeptide Hormone Activity	G Protein-coupled Receptor Activity Somatostatin Receptor Activity Peptide Binding Neuropeptide Binding
	Biological Process	Resolution Of Meiotic Recombination Intermediates Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Chemical Synaptic Transmission Replication Fork Processing	G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Neuropeptide Signaling Pathway Negative Regulation Of Cell Population Proliferation Cell Migration Forebrain Development Somatostatin Signaling Pathway Positive Regulation Of ERK1 And ERK2 Cascade Cellular Response To Glucocorticoid Stimulus Positive Regulation Of Arachidonic Acid Secretion Negative Regulation Of Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway
Pathways		Peptide ligand-binding receptors G alpha (i) signalling events	Peptide ligand-binding receptors G alpha (i) signalling events
Drugs			Somatostatin Lutetium Lu 177 dotatate
Diseases
GWAS		Male-pattern baldness ( 28196072)	Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653) Amyotrophic lateral sclerosis (sporadic) ( 24529757) Blood sugar levels ( 29403010) Hypothyroidism ( 27182965) Mitochondrial DNA copy number ( 30704525) Obesity-related traits ( 23251661) Vitamin D levels ( 26704534)
Interacting Genes		7 interacting genes: GHSR MRGPRX2 SSTR1 SSTR2 SSTR3 SSTR4 SSTR5	2 interacting genes: CORT SST
Entrez ID		1325	6754
HPRD ID		04150	01676
Ensembl ID		ENSG00000241563	ENSG00000132671
Uniprot IDs		O00230 Q8IUV6	P31391
PDB IDs
Enriched GO Terms of Interacting Partners?
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