COPA and SCYL1

Number of citations of the paper that reports this interaction (PubMedID 30631079)
12

Data Source:
BioGRID (pull down)

		COPA	SCYL1
Description		COPI coat complex subunit alpha	SCY1 like pseudokinase 1
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Extracellular Space Cytoplasm Endoplasmic Reticulum Membrane Cytosol Membrane COPI Vesicle Coat Transport Vesicle Growth Cone Extracellular Exosome	Nucleus Cytoplasm Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Cis-Golgi Network Microtubule Organizing Center Cytosol Membrane COPI Vesicle Coat
	Molecular Function	Hormone Activity Structural Molecule Activity Protein Binding	DNA Binding Protein Tyrosine Kinase Activity ATP Binding Cadherin Binding
	Biological Process	Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Intra-Golgi Vesicle-mediated Transport Signal Transduction Pancreatic Juice Secretion	Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Inflammatory Response Peptidyl-tyrosine Phosphorylation Spinal Cord Motor Neuron Differentiation Cellular Protein Localization Neuron Development
Pathways		COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic
Drugs			Grn163l
Diseases
GWAS		Breast size ( 27182965)	Acne (severe) ( 24927181) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Femoral neck bone mineral density ( 22504420) Hip index ( 34021172) Refractive error ( 32231278) Vertical cup-disc ratio ( 20548946)
Interacting Genes		18 interacting genes: ARCN1 ARFGAP1 CDC42 COPB2 COPE DUX4 MTNR1B PDGFRB PTEN SACM1L SCYL1 SLC25A11 STX8 SUMO2 TMED10 TMED2 WBP1 WBP2	23 interacting genes: APP ARCN1 ARF1 ARF3 AXIN1 CCNF CD93 CDC25A CHD1L COIL COPA COPB1 COPE COPG1 DAPK1 DDX6 GORAB LENG1 NOD2 PIN1 PLEKHF2 SMURF1 TCEA2
Entrez ID		1314	57410
HPRD ID		03564	06414
Ensembl ID		ENSG00000122218	ENSG00000142186
Uniprot IDs		P53621	E9PK59 Q96KG9
PDB IDs		6PBG 6TZT 6U3V
Enriched GO Terms of Interacting Partners?
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