TTC32 and PRDM14

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		TTC32	PRDM14
Description		tetratricopeptide repeat domain 32	PR/SET domain 14
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Nucleus Nucleoplasm
	Molecular Function	Protein Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Binding Protein Binding Methyltransferase Activity Chromatin DNA Binding Metal Ion Binding
	Biological Process		Negative Regulation Of Transcription By RNA Polymerase II Cell Morphogenesis Cell Fate Specification Inner Cell Mass Cell Fate Commitment Regulation Of Transcription By RNA Polymerase II Germ Cell Development Embryo Implantation Fertilization Regulation Of Gene Expression Germ-line Stem Cell Population Maintenance Histone H3-R26 Methylation Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of DNA Methylation Homeostasis Of Number Of Cells Within A Tissue Inactivation Of Paternal X Chromosome Positive Regulation Of Flagellated Sperm Motility Positive Regulation Of Stem Cell Population Maintenance
Pathways			Transcriptional regulation of pluripotent stem cells
Drugs
Diseases
GWAS		Coronary artery disease ( 32469254) Coronary heart disease ( 22751097) Metabolite levels ( 23823483) Monobrow ( 27182965) Myocardial infarction ( 33532862)	Schizophrenia ( 30285260) Testicular germ cell tumor ( 28604728 28604732 23666240)
Interacting Genes		10 interacting genes: ARID3A FBF1 MAGED1 MYOG NCAPH2 PRDM14 TRIM39 TXN2 ZNF18 ZNF219	68 interacting genes: ABI2 AKAP9 AQP1 ATPAF2 BAG4 BAHD1 BCAR3 BEX2 CARD10 CASP8 CBFA2T2 CDCA7L CHEK2 CREB5 DGCR6 DMRT3 EED EIF4E2 ENKD1 ERBB2 EZH2 FAM83A GAS8 GEM GLYCTK GPATCH2L HEXIM2 HOXB5 HOXC8 HSPB7 ID3 IDH1 KANK2 LNX1 MIA3 MRPL32 MYPOP NDUFB9 PALB2 PATZ1 PAX2 PLEKHF2 PPP1R32 PRKAB2 PRPF31 PSMA1 PTPRJ RAD51D RBM10 RCOR3 RUNX1T1 RUSC1 SCNM1 SNRPC SUZ12 TCAF1 TEAD4 TEKT4 TLE5 TRIM41 TSGA10 TTC32 TXK USP2 WDR25 ZNF250 ZNF587 ZNF835
Entrez ID		130502	63978
HPRD ID		17296	11457
Ensembl ID		ENSG00000183891	ENSG00000147596
Uniprot IDs		Q5I0X7	Q9GZV8
PDB IDs
Enriched GO Terms of Interacting Partners?
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