ICA1L and TNPO3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ICA1L	TNPO3
Description		islet cell autoantigen 1 like	transportin 3
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus	Nuclear Envelope Annulate Lamellae Cytoplasm Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Protein Domain Specific Binding	Protein Binding Small GTPase Binding Identical Protein Binding Nuclear Import Signal Receptor Activity
	Biological Process	Regulation Of Transport	Protein Import Into Nucleus
Pathways
Drugs
Diseases
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Heel bone mineral density ( 28869591) Ischemic stroke (small-vessel) ( 29531354) Lacunar stroke ( 33773637) Mean platelet volume ( 32888494) Microalbuminuria ( 31511532) Non-lobar intracerebral hemorrhage (MTAG) ( 31430377) Platelet count ( 32888494) Spontaneous coronary artery dissection ( 32887874) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Urinary albumin excretion ( 30220432) Urinary albumin-to-creatinine ratio ( 31630189 31511532) White matter hyperintensities ( 32358547) White matter integrity (fractional anisotropy) ( 32358547)	Diffuse cutaneous systemic sclerosis ( 29293537) Limited cutaneous systemic scleroderma ( 29293537) Platelet count ( 32888494) Plateletcrit ( 32888494) Primary biliary cholangitis ( 20639880) Primary biliary cirrhosis ( 22961000) SjÃ¶gren's syndrome ( 24097067) Systemic lupus erythematosus ( 18204446 24871463 26606652 23053960 26502338 18204098 32771030 28714469) Systemic lupus erythematosus and Systemic sclerosis ( 23740937) Systemic lupus erythematosus or rheumatoid arthritis ( 27193031) Systemic sclerosis ( 21750679 31672989 30247649 29293537) Systemic sclerosis (anti-centromere-positive) ( 29293537) Systemic sclerosis (anti-topoisomerase-positive) ( 29293537) Systemic seropositive rheumatic diseases (Systemic sclerosis or systemic lupus erythematosus or rheumatoid arthritis or idiopathic inflammatory myopathies) ( 30573655) Ulcerative colitis ( 23128233 21297633)
Interacting Genes		14 interacting genes: DPY30 FAM117B FLACC1 GCC1 HGS KCTD18 KIFC3 KRT27 LMO2 MARS2 MTDH RCOR3 RFTN2 TNPO3	19 interacting genes: BLMH CAMK2B CAMK2D CAMK2G CHMP3 CLPP ECI2 GCH1 ICA1L KRT75 KRTAP10-8 MEOX2 NME1 PPP1R1C SMURF2 SRSF1 SSX2 SSX2B TRA2B
Entrez ID		130026	23534
HPRD ID		12447	18209
Ensembl ID		ENSG00000163596	ENSG00000064419
Uniprot IDs		A0A024R3W3 Q8NDH6 Q96Q33	A0A024R794 B3KMX1 Q9Y5L0
PDB IDs			4C0O 4C0P 4C0Q 4OL0 6GX9
Enriched GO Terms of Interacting Partners?
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