TAF8 and TAF7

Number of citations of the paper that reports this interaction (PubMedID 14580349)
21

Data Source:
HPRD (in vitro, in vivo)

		TAF8	TAF7
Description		TATA-box binding protein associated factor 8	TATA-box binding protein associated factor 7
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Factor TFIID Complex Perinuclear Region Of Cytoplasm	Nucleoplasm Transcription Regulator Complex Transcription Factor TFIID Complex Cytoplasm Transcription Factor TFTC Complex MLL1 Complex
	Molecular Function	Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity Protein Heterodimerization Activity	Transcription Cis-regulatory Region Binding TFIIH-class Transcription Factor Complex Binding Protein Binding Transcription Factor Binding RNA Polymerase II General Transcription Initiation Factor Activity Histone Acetyltransferase Binding Vitamin D Receptor Binding Thyroid Hormone Receptor Binding Protein Heterodimerization Activity H3K27me3 Modified Histone Binding P-TEFb Complex Binding
	Biological Process	DNA-templated Transcription Open Complex Formation Inner Cell Mass Cell Proliferation Transcription Initiation From RNA Polymerase II Promoter Cell Differentiation Regulation Of Fat Cell Differentiation Maintenance Of Protein Location In Nucleus	Negative Regulation Of Transcription By RNA Polymerase II Spermine Transport DNA-templated Transcription, Initiation Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Negative Regulation Of Protein Kinase Activity Intracellular Estrogen Receptor Signaling Pathway Negative Regulation Of Histone Acetylation Negative Regulation Of MHC Class I Biosynthetic Process Negative Regulation Of MHC Class II Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II RNA Polymerase II Preinitiation Complex Assembly Negative Regulation Of Histone H4 Acetylation
Pathways		RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes	HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome RNA Polymerase II Pre-transcription Events Regulation of TP53 Activity through Phosphorylation RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance
Drugs
Diseases
GWAS		Exploratory eye movement dysfunction in schizophrenia (cognitive search score) ( 26242244) Exploratory eye movement dysfunction in schizophrenia (number of eye fixations) ( 26242244) Exploratory eye movement dysfunction in schizophrenia (responsive search score) ( 26242244) HDL cholesterol levels ( 28334899) Hemoglobin levels ( 33491795) Lymphocyte counts ( 32888494) Lymphocyte percentage of white cells ( 32888494) Mosaic loss of chromosome Y (Y chromosome dosage) ( 31624269) Neutrophil percentage of white cells ( 32888494)	Mean platelet volume ( 32888494 27863252) Refractive error ( 32231278)
Interacting Genes		15 interacting genes: H3-4 KPNA2 KPNB1 RSPH9 TAF1 TAF10 TAF11 TAF12 TAF2 TAF4 TAF5 TAF6 TAF7 TAF9 TCTE1	28 interacting genes: AHR CDK7 CDK9 CPSF1 FAU GATA1 H3-4 HSF1 IKBKG MAP1LC3B OGT RBM6 SETD7 TAF1 TAF10 TAF11 TAF12 TAF15 TAF2 TAF4 TAF5 TAF6 TAF8 TAF9 TRIM22 TRIM24 YWHAE ZSCAN1
Entrez ID		129685	6879
HPRD ID		18167	07196
Ensembl ID		ENSG00000137413	ENSG00000178913
Uniprot IDs		Q7Z7C8	Q15545
PDB IDs		4WV4 4WV6 5FUR 6MZC 6MZL 6MZM	4RGW 5FUR 6MZL 6MZM
Enriched GO Terms of Interacting Partners?
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