JOSD2 and AHCYL1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		JOSD2	AHCYL1
Description		Josephin domain containing 2	adenosylhomocysteinase like 1
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GO Annotations	Cellular Component	Cytosol	Cytoplasm Endoplasmic Reticulum Membrane Cytosol Apical Plasma Membrane Mitochondria-associated Endoplasmic Reticulum Membrane Extracellular Exosome
	Molecular Function	Thiol-dependent Deubiquitinase Protein Binding	RNA Binding Adenosylhomocysteinase Activity Protein Binding Identical Protein Binding
	Biological Process	Protein Deubiquitination	MRNA Polyadenylation Protein Export From Nucleus One-carbon Metabolic Process Apoptotic Process Positive Regulation Of Sodium Ion Transport Regulation Of MRNA 3'-end Processing Regulation Of Ion Transmembrane Transporter Activity S-adenosylmethionine Cycle Angiotensin-activated Signaling Pathway Epithelial Fluid Transport Regulation Of Anion Transport Response To Calcium Ion Mitochondrion-endoplasmic Reticulum Membrane Tethering
Pathways		Josephin domain DUBs	PLC beta mediated events DAG and IP3 signaling Role of phospholipids in phagocytosis FCERI mediated Ca+2 mobilization Regulation of insulin secretion VEGFR2 mediated cell proliferation Ion homeostasis Ion homeostasis CLEC7A (Dectin-1) induces NFAT activation FCGR3A-mediated IL10 synthesis Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
Drugs
Diseases
GWAS			Height ( 31562340)
Interacting Genes		13 interacting genes: AHCYL1 CMTM5 COQ8A FKBP7 MDK PLA2G2A STUB1 SYP TRAPPC2 TRAPPC2B TTPA UBC YIF1A	25 interacting genes: BID CDKN2C DACH1 GEM HBQ1 HEXIM2 HGS HSPA6 ITPR1 JOSD2 LRRK2 MEOX2 MFHAS1 PLEKHG5 PPL PRDM6 PSMD9 RNF6 SLC23A1 SOX30 SRPK1 SRPK2 SUMO2 UACA ZNF165
Entrez ID		126119	10768
HPRD ID		15297	07613
Ensembl ID		ENSG00000161677	ENSG00000168710
Uniprot IDs		A0A024R4G2 Q7Z7N5 Q8TAC2	A0A024R0A8 O43865
PDB IDs		6PGV	3MTG
Enriched GO Terms of Interacting Partners?
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