DCUN1D3 and UBE2M

Number of citations of the paper that reports this interaction (PubMedID 28581483)
29

Data Source:
BioGRID (pull down)

		DCUN1D3	UBE2M
Description		defective in cullin neddylation 1 domain containing 3	ubiquitin conjugating enzyme E2 M
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GO Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleus Cytoplasm Plasma Membrane Perinuclear Region Of Cytoplasm	Nucleus Nucleoplasm Cytosol
	Molecular Function	Molecular_function Protein Binding Ubiquitin Conjugating Enzyme Binding Ubiquitin-like Protein Binding Cullin Family Protein Binding	Ubiquitin-protein Transferase Activity Protein Binding ATP Binding NEDD8 Transferase Activity
	Biological Process	Response To UV-C Response To Gamma Radiation Regulation Of Cell Cycle Process Negative Regulation Of Cell Growth Positive Regulation Of Apoptotic Process Protein Neddylation Positive Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Protein Neddylation Negative Regulation Of Protein Neddylation Positive Regulation Of Protein Neddylation	Cellular Protein Modification Process Protein Ubiquitination Positive Regulation Of Neuron Apoptotic Process Post-translational Protein Modification Protein Neddylation
Pathways		Neddylation	TGF-beta receptor signaling activates SMADs Dectin-1 mediated noncanonical NF-kB signaling NIK-->noncanonical NF-kB signaling Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Hippocampal sclerosis ( 25188341)	Mean corpuscular hemoglobin ( 32888494)
Interacting Genes		3 interacting genes: CUL2 CUL3 UBE2M	32 interacting genes: APP CAND1 CBL CFL1 CPNE1 CPNE2 CPNE4 CUL1 CUL4A CUL7 DCUN1D1 DCUN1D2 DCUN1D3 DCUN1D4 DCUN1D5 FBXO7 HSPA4 ITCH MARCHF7 NEDD4 NEDD8 PINK1 PRKN RBX1 RNF111 RNF7 SENP8 SMURF1 TERF1 TP53 UBA1 UBA3
Entrez ID		123879	9040
HPRD ID		14660	04414
Ensembl ID		ENSG00000188215	ENSG00000130725
Uniprot IDs		Q8IWE4	A0A024R4T4 P61081
PDB IDs		4GBA	1TT5 1Y8X 2NVU 3TDU 3TDZ 4GAO 4P5O
Enriched GO Terms of Interacting Partners?
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