LRRK2 and STAC

  • Number of citations of the paper that reports this interaction (PubMedID 24510904)
  • 161

LRRK2

STAC

Description leucine rich repeat kinase 2 SH3 and cysteine rich domain
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Age-related cognitive decline (global cognition) (slope of z-scores) ( 30954325)
  • Age-related cognitive decline (language) (slope of z-scores) ( 30954325)
  • Arterial stiffness (brachial-femoral pulse wave velocity) ( 32790701)
  • Asthma ( 29273806)
  • Brooding (response to stress) ( 30886212)
  • Celiac disease ( 23936387)
  • Erectile dysfunction in type 1 diabetes ( 22704111)
  • Itch intensity from mosquito bite adjusted by bite size ( 28199695)
  • Kidney disease (end stage renal disease vs non-end stage renal disease) in type 1 diabetes ( 31537649)
  • Metabolite levels ( 23823483)
  • Smoking behaviour (maximum cigarettes in a 24 hour period) ( 29532581)
Interacting Genes 146 interacting genes: ABLIM1 ACTB AFF4 AHCYL1 AHDC1 AKT1 ANKS4B ANO6 APEX2 APP ARFGAP1 ARHGEF7 AURKB BAG1 BAG2 BAG3 C18orf25 C1orf87 CAMK1D CBLB CCDC43 CDC42EP3 CDKL3 CETN3 CHGB CRMP1 CUEDC1 CXCL11 CYREN DBF4B DDIT4 DIDO1 DUX3 DVL1 DVL2 DVL3 DYRK2 E2F4 ECHS1 EIF4EBP1 ENKUR ESRRG FAM184A FAM47B FAM90A1 FANCM FCHSD1 GTSF1 HIF1A HSPD1 ITGB3BP JHY KCTD18 KDM4D KLC2 L3MBTL3 LARP4 LARP7 LATS1 LGALS8 LINC01139 LRP6 MAP1B MAP2K3 MAP2K4 MAP2K6 MAP2K7 MAPT MATK MBP MLLT3 MRGBP MRPL19 MRPL28 MTA1 MYL9 NCBP3 NDUFAF7 NEK1 NSL1 PADI4 PDCL PHF20L1 PIK3CB PIK3R1 PLK1 POLR2M POU5F1 PPP1R8 PRICKLE1 PRKCZ PSME3IP1 PTPN23 RAB11FIP2 RAD51AP1 RALYL RAPGEF4 RASL11B RBIS RHBDD1 RIPK2 RIT1 RPAP3 RPS6KB2 SCEL SERF1A SH3GL2 SH3GL3 SKA3 SMTNL2 SPATS2 SQSTM1 STAC STK24 STK25 STK3 STK40 STN1 STRBP STUB1 SUPT4H1 SYNJ1 TAOK3 TAS2R60 TBC1D22B TCEA2 TCP10L TGIF2LX TRAF2 TTC27 TTLL1 TUBA1A UBXN10 UFD1 UQCRB USP39 VASH2 VGLL4 VN1R1 WSB1 WT1-AS XIRP2 ZAP70 ZFAND5 ZMYM5 ZRANB2 22 interacting genes: APP FBXO25 GOLGA2 KANK2 KIAA1958 LIMD1 LMNA LRRK2 LZTS2 MEOX2 NBPF19 NCKIPSD NEDD4L NOTCH2NLA PAX5 PAX6 PJA1 POU6F2 RNF208 STAT5B TRIP6 TRMO
Entrez ID 120892 6769
HPRD ID 10613 11890
Ensembl ID ENSG00000188906 ENSG00000144681
Uniprot IDs Q17RV3 Q5S007 B4DR96 B4DZ13 E9PEA7 Q8WUK8 Q99469
PDB IDs 2ZEJ 3D6T 5MY9 5MYC 6DLO 6DLP 6OJE 6OJF 6VNO 6VP6 6VP7 6XR4 2DL4 6B25
Enriched GO Terms of Interacting Partners?
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