ADD2 and PTPRZ1

Number of citations of the paper that reports this interaction (PubMedID 16105548)
21

Data Source:
HPRD (in vivo)

		ADD2	PTPRZ1
Description		adducin 2	protein tyrosine phosphatase receptor type Z1
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Cytoskeleton Plasma Membrane F-actin Capping Protein Complex Postsynaptic Density Cytoplasmic Vesicle Plasma Membrane Raft	Extracellular Region Plasma Membrane Integral Component Of Plasma Membrane Intrinsic Component Of Plasma Membrane Synapse Perineuronal Net
	Molecular Function	Actin Binding Structural Constituent Of Cytoskeleton Calmodulin Binding Protein Kinase Binding Spectrin Binding Protein Homodimerization Activity Protein Heterodimerization Activity Actin Filament Binding	Protein Tyrosine Phosphatase Activity Transmembrane Receptor Protein Tyrosine Phosphatase Activity Integrin Binding Protein Binding
	Biological Process	Synapse Assembly Actin Cytoskeleton Organization Hemopoiesis Positive Regulation Of Protein Binding Leukocyte Migration Leukocyte Tethering Or Rolling Barbed-end Actin Filament Capping Actin Filament Bundle Assembly Protein-containing Complex Assembly	Hematopoietic Progenitor Cell Differentiation Protein Dephosphorylation Axonogenesis Central Nervous System Development Learning Or Memory Regulation Of Myelination Peptidyl-tyrosine Dephosphorylation Negative Regulation Of Neuron Apoptotic Process Oligodendrocyte Differentiation Positive Regulation Of Oligodendrocyte Differentiation Regulation Of Oligodendrocyte Progenitor Proliferation
Pathways		Miscellaneous transport and binding events	Signaling by ALK Other interleukin signaling
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Response to esketamine in treatment resistant depression ( 32724131)	Hand grip strength ( 27325353) Heel bone mineral density ( 30598549) Lung adenocarcinoma ( 28604730)
Interacting Genes		9 interacting genes: ADD1 APP BRWD1 CALM1 FYN PRKACA PRKCD PTPRZ1 RPH3A	16 interacting genes: AASS ADD2 ALK ARHGAP35 BMP1 CTNNB1 FYN GIT1 HMGB1 IL34 MDK MGAT5B NMB PTN PTPRF TNR
Entrez ID		119	5803
HPRD ID		00037	01481
Ensembl ID		ENSG00000075340	ENSG00000106278
Uniprot IDs		P35612 Q05DK5	B4DFE7 P23471
PDB IDs			3JXF 3S97 5AWX 5H08
Enriched GO Terms of Interacting Partners?
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