PHACTR3 and CAPNS2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

		PHACTR3	CAPNS2
Description		phosphatase and actin regulator 3	calpain small subunit 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nuclear Matrix	Cytosol Plasma Membrane
	Molecular Function	Actin Binding Protein Phosphatase Inhibitor Activity Protein Binding Protein Phosphatase 1 Binding	Calcium-dependent Cysteine-type Endopeptidase Activity Calcium Ion Binding Protein Binding
	Biological Process	Actin Cytoskeleton Organization Negative Regulation Of Catalytic Activity	Proteolysis
Pathways			Degradation of the extracellular matrix Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
Drugs
Diseases
GWAS		Disease progression in age-related macular degeneration (adjusted for baseline) ( 29346644) General cognitive ability ( 29844566) Intelligence (MTAG) ( 29326435) Refractive error ( 32231278) Rheumatoid arthritis ( 30891314) Schizophrenia ( 30285260)	Thyroid hormone levels ( 23408906)
Interacting Genes		10 interacting genes: CAPNS2 CYB5B EEF1G MAPK6 PLPP6 PPP1CA PPP1CB TAB1 UBIAD1 UBL5	9 interacting genes: APP ARMC10 CAPN2 CMTM5 OXNAD1 PHACTR3 PPIC PRPF31 RIN1
Entrez ID		116154	84290
HPRD ID		10571	16682
Ensembl ID		ENSG00000087495	ENSG00000256812
Uniprot IDs		B7Z339 Q96KR7	Q96L46
PDB IDs
Enriched GO Terms of Interacting Partners?
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