FAM210B and HEXB

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		FAM210B	HEXB
Description		family with sequence similarity 210 member B	hexosaminidase subunit beta
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Integral Component Of Membrane Intrinsic Component Of Membrane	Acrosomal Vesicle Extracellular Region Lysosome Membrane Azurophil Granule Lumen Azurophil Granule Lysosomal Lumen Cortical Granule Extracellular Exosome
	Molecular Function	Protein Binding	Beta-N-acetylhexosaminidase Activity Protein Binding Acetylglucosaminyltransferase Activity Identical Protein Binding N-acetyl-beta-D-galactosaminidase Activity
	Biological Process	Erythrocyte Maturation Positive Regulation Of Erythrocyte Differentiation Cellular Response To Estradiol Stimulus	Skeletal System Development Ganglioside Catabolic Process Cellular Calcium Ion Homeostasis Lysosome Organization Single Fertilization Penetration Of Zona Pellucida Sensory Perception Of Sound Locomotory Behavior Male Courtship Behavior Regulation Of Cell Shape Phospholipid Biosynthetic Process Oligosaccharide Catabolic Process Lipid Storage Glycosaminoglycan Metabolic Process Myelination Astrocyte Cell Migration Cellular Protein Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Oogenesis Neuromuscular Process Controlling Balance
Pathways			Glycosphingolipid metabolism Keratan sulfate degradation CS/DS degradation Hyaluronan uptake and degradation Defective HEXB causes GM2G2 Neutrophil degranulation
Drugs			Pyrimethamine 2-Acetamido-2-Deoxy-D-Glucono-1,5-Lactone N-Acetyl-glucosamine thiazoline (2R,3R,4S,5R)-2-acetamido-3,4-dihydroxy-5-hydroxymethyl-piperidine
Diseases
GWAS			Gut microbiota relative abundance (unassigned genus belonging to family Clostridiales) ( 33208821) Metabolite levels ( 23823483) Night sleep phenotypes ( 27126917)
Interacting Genes		62 interacting genes: ATP6V0B ATP6V0C BCL2L13 BET1 C1GALT1 C5orf46 CCDC167 CD300C CLDND2 CNIH3 CYB5B CYB5R3 CYP4F2 EMP3 FIS1 FXYD6-FXYD2 GIMAP5 HEXB HMOX1 HMOX2 IER3IP1 IFITM3 LNPEP LPAR3 MFF MS4A13 NINJ2 NKG7 ORMDL2 OTOP3 PLP2 PLPP6 RPRM RTP2 SERP1 SERP2 SLC16A13 SLC30A8 SLC35B4 SLC35G1 SMCO4 SMIM1 STX6 STX7 SYNJ2BP TF TFRC TIMM23 TIMMDC1 TMEM107 TMEM11 TMEM140 TMEM187 TMEM19 TMIE UBE2J1 VAMP1 VAMP3 VAMP4 VKORC1 YIF1A ZDHHC21	5 interacting genes: CSNK2B EIF2D FAM210B HOXA1 TMEM14B
Entrez ID		116151	3074
HPRD ID		12737	06043
Ensembl ID		ENSG00000124098	ENSG00000049860
Uniprot IDs		Q96KR6	A0A024RAJ6 P07686 Q5URX0
PDB IDs			1NOU 1NOW 1NP0 1O7A 1QBD 2GJX 2GK1 3LMY 5BRO
Enriched GO Terms of Interacting Partners?
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