FCRL3 and STATH

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		FCRL3	STATH
Description		Fc receptor like 3	statherin
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Plasma Membrane Cell Surface	Extracellular Region
	Molecular Function	Transmembrane Signaling Receptor Activity Kinase Binding Phosphatase Binding Protein Phosphatase Binding Protein Tyrosine Kinase Binding	Protein Binding Extracellular Matrix Constituent, Lubricant Activity Structural Constituent Of Tooth Enamel Hydroxyapatite Binding
	Biological Process	Negative Regulation Of Immunoglobulin Production Cell Surface Receptor Signaling Pathway Positive Regulation Of B Cell Proliferation Regulation Of Toll-like Receptor 9 Signaling Pathway Positive Regulation Of MAPK Cascade Regulation Of B Cell Differentiation Negative Regulation Of B Cell Receptor Signaling Pathway Regulation Of B Cell Activation Regulation Of Calcium Ion Import Positive Regulation Of Protein Serine/threonine Phosphatase Activity	Ossification Negative Regulation Of Bone Mineralization Biomineral Tissue Development Defense Response To Bacterium Saliva Secretion
Pathways
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488 28240269) Graves' disease ( 21841780) IgA nephropathy ( 32912934 26028593) Insulinoma-associated antigen 2 autoantibody levels in type 1 diabetes ( 21829393) Multiple sclerosis ( 31604244 21833088) Multiple sclerosis and LDL levels (pleiotropy) ( 26920376) Rheumatoid arthritis ( 30423114 24390342) Rheumatoid arthritis (ACPA-positive) ( 24532676) Selective IgA deficiency ( 27723758)
Interacting Genes		12 interacting genes: AGPAT4 CMTM5 FCRL1 IGFBP5 MS4A1 PTPN11 PTPN6 SLC2A5 SLC30A3 STATH SYK ZAP70	25 interacting genes: AQP6 C16orf92 DERL3 ERGIC3 FAM209A FCRL3 GET3 GPR152 GPR42 KCNJ6 LEUTX MFSD5 MRM1 MTIF3 OPRPN OVGP1 REEP4 SGPL1 SLC10A6 SLC39A2 SPNS3 TFAM TLCD4 TMEM80 TMX2
Entrez ID		115352	6779
HPRD ID		07352	01696
Ensembl ID		ENSG00000160856	ENSG00000126549
Uniprot IDs		Q96P31	P02808
PDB IDs
Enriched GO Terms of Interacting Partners?
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