TOE1 and RPS3A

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		TOE1	RPS3A
Description		target of EGR1, exonuclease	ribosomal protein S3A
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GO Annotations	Cellular Component	Nucleoplasm Nucleolus Cytoplasm Cajal Body Nuclear Body Nuclear Speck	Nucleus Nucleoplasm Nucleolus Cytoplasm Endoplasmic Reticulum Cytosol Focal Adhesion Cytosolic Ribosome Cytosolic Small Ribosomal Subunit Extracellular Exosome Ribonucleoprotein Complex
	Molecular Function	3'-5'-exoribonuclease Activity RNA Binding Poly(A)-specific Ribonuclease Activity Protein Binding SnRNA Binding Metal Ion Binding	RNA Binding Structural Constituent Of Ribosome Protein Binding MRNA 5'-UTR Binding
	Biological Process	SnRNA 3'-end Processing RNA Phosphodiester Bond Hydrolysis, Exonucleolytic	Cytoplasmic Translation Translation Translational Initiation Cell Differentiation Negative Regulation Of Apoptotic Process
Pathways			L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS			HDL cholesterol ( 20686565)
Interacting Genes		26 interacting genes: ABCF3 AGGF1 AP2A1 APLP1 CA12 HNRNPF IK IL7R LSM4 OGT PPP1CA PRCC RAB40C RBM39 RBM8A RPS3A SF3B2 SF3B3 SH3GL3 SQSTM1 SRSF6 SUMO1 U2AF1 UNC13B WDR77 WDR83	20 interacting genes: ATF7IP C11orf49 CCDC50 CHN1 CREB3 DDIT3 DUX4 EDEM2 FANCC HGS HSP90AA1 LINC01232 NEDD4 OGT PARP1 SAP18 SOD2 TOE1 UBE2I VDAC2
Entrez ID		114034	6189
HPRD ID		18212	01606
Ensembl ID		ENSG00000132773	ENSG00000145425
Uniprot IDs		Q96GM8	B7Z3M5 P61247
PDB IDs		2FC6	4UG0 4V6X 5A2Q 5AJ0 5FLX 5LKS 5OA3 5T2C 5VYC 6EK0 6FEC 6G18 6G4S 6G4W 6G51 6G53 6G5H 6G5I 6IP5 6IP6 6IP8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP 6XA1 6Y0G 6Y2L 6Y57 6YBD 6YBW 6Z6L 6Z6M 6Z6N 6ZLW 6ZM7 6ZME 6ZMI 6ZMO 6ZMT 6ZMW 6ZN5 6ZOJ 6ZOK 6ZON 6ZP4 6ZVH 6ZVJ 6ZXD 6ZXE 6ZXF 6ZXG 6ZXH 7A09 7K5I
Enriched GO Terms of Interacting Partners?
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