KLHDC7B and SMUG1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		KLHDC7B	SMUG1
Description		kelch domain containing 7B	single-strand-selective monofunctional uracil-DNA glycosylase 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Fibrillar Center Nucleoplasm Nucleolus Cytosol
	Molecular Function	Protein Binding	Oxidized Pyrimidine Nucleobase Lesion DNA N-glycosylase Activity DNA Binding Uracil DNA N-glycosylase Activity Protein Binding Single-strand Selective Uracil DNA N-glycosylase Activity DNA N-glycosylase Activity
	Biological Process		Base-excision Repair Depyrimidination
Pathways			Recognition and association of DNA glycosylase with site containing an affected pyrimidine Cleavage of the damaged pyrimidine Displacement of DNA glycosylase by APEX1
Drugs
Diseases
GWAS		Mean corpuscular hemoglobin ( 20139978) Monocyte count ( 32888494) Red blood cell count ( 29403010) Serum metabolite levels ( 33031748)	Coronary artery disease ( 32469254) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		24 interacting genes: A1CF BHLHE40 DTX2 ESRP1 FNDC3B HNRNPUL1 LIMS3 LIMS4 MAPRE3 NFYC PATZ1 PHC2 POGZ QRICH1 RBPMS RBPMS2 RHOXF2 SMUG1 TBX6 TEX37 TLE5 TP53BP1 WWOX ZC3H10	37 interacting genes: C10orf55 CDC23 CRX CYSRT1 GLYCTK GPS2 HNRNPF INCA1 KCTD9 KLHDC7B KRTAP13-2 KRTAP15-1 KRTAP26-1 KRTAP6-2 KRTAP8-1 LMO2 MGAT5B NEK6 NOXA1 PEF1 PRKAB2 PROP1 PRR13 PRR35 RBPMS SKIL SMARCD1 SPAG8 TCF7L2 TEKT5 TFG TRAPPC6A TRIP13 VAC14 VENTX YPEL3 ZIC1
Entrez ID		113730	23583
HPRD ID		14453	06376
Ensembl ID		ENSG00000130487	ENSG00000123415
Uniprot IDs		Q96G42	A0A024RAZ8 A0A0S2Z526 Q53HV7
PDB IDs
Enriched GO Terms of Interacting Partners?
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