EXOC3 and BIRC6

Number of citations of the paper that reports this interaction (PubMedID 18329369)
83

Data Source:
HPRD (in vivo)

		EXOC3	BIRC6
Description		exocyst complex component 3	baculoviral IAP repeat containing 6
Image		No pdb structure
GO Annotations	Cellular Component	Exocyst Golgi Apparatus Cytosol Growth Cone Midbody Secretory Granule Membrane Presynaptic Membrane Perinuclear Region Of Cytoplasm	Spindle Pole Nucleus Endosome Trans-Golgi Network Microtubule Organizing Center Membrane Midbody Flemming Body
	Molecular Function	SNARE Binding Protein Binding Cadherin Binding	Ubiquitin-protein Transferase Activity Cysteine-type Endopeptidase Inhibitor Activity Protein Binding Ubiquitin Conjugating Enzyme Activity
	Biological Process	Exocytosis Protein Transport Exocyst Localization	Protein Phosphorylation Ubiquitin-dependent Protein Catabolic Process Apoptotic Process Cell Cycle Positive Regulation Of Cell Population Proliferation Negative Regulation Of Endopeptidase Activity Protein Ubiquitination Regulation Of Cytokinesis Regulation Of Cell Population Proliferation Negative Regulation Of Apoptotic Process Cell Division Labyrinthine Layer Development Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane Insulin processing VxPx cargo-targeting to cilium	ALK mutants bind TKIs Signaling by ALK fusions and activated point mutants
Drugs
Diseases
GWAS		Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin concentration ( 27863252) Hemoglobin levels ( 32327693) Hypospadias ( 25108383) Red blood cell count ( 32888494) Ulcerative colitis ( 21297633)	Chronotype ( 30696823) Coffee consumption ( 31046077) General risk tolerance (MTAG) ( 30643258) Male-pattern baldness ( 28196072) Red cell distribution width ( 32888494) Refractive error ( 32231278) Risk-taking tendency (4-domain principal component model) ( 30643258)
Interacting Genes		12 interacting genes: APP BIRC6 BUB3 EXOC2 FSD2 GMCL1 MAILR MLH1 PPP1R12C RALA TERT VAMP2	23 interacting genes: ALK BIRC5 CASP3 CASP7 CASP8 CASP9 CDK1 CSNK2A1 DIABLO EXOC3 EXOC4 GABARAP HTRA2 MAP1LC3B MAP2K1 PLK1 RAB8A RACK1 RNF41 UBE2D1 USP8 VAV2 VCL
Entrez ID		11336	57448
HPRD ID		09738	05731
Ensembl ID		ENSG00000180104	ENSG00000115760
Uniprot IDs		A0A024QYZ6 O60645 Q69YP2	Q9NR09
PDB IDs			3CEG
Enriched GO Terms of Interacting Partners?
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