CBX3 and RAD54L2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CBX3	RAD54L2
Description		chromobox 3	RAD54 like 2
Image			No pdb structure
GO Annotations	Cellular Component	Chromosome, Centromeric Region Condensed Chromosome, Centromeric Region Chromosome, Telomeric Region Chromatin Euchromatin Heterochromatin Nucleus Nuclear Envelope Nuclear Inner Membrane Nucleoplasm Pericentric Heterochromatin Spindle RNA Polymerase II Transcription Regulator Complex Site Of DNA Damage	Nucleus
	Molecular Function	Transcription Coregulator Binding Protein Binding Enzyme Binding Protein Domain Specific Binding Identical Protein Binding Histone Methyltransferase Binding	DNA Binding DNA Helicase Activity Protein Binding ATP Binding ATP Hydrolysis Activity ATP-dependent Chromatin Remodeler Activity
	Biological Process	Chromatin Remodeling Cellular Response To DNA Damage Stimulus Negative Regulation Of Transcription, DNA-templated Rhythmic Process	DNA Duplex Unwinding
Pathways		ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression RNA Polymerase I Promoter Escape Transcriptional Regulation by E2F6
Drugs
Diseases
GWAS		Metabolite levels ( 23823483) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Estimated glomerular filtration rate ( 31152163)
Interacting Genes		44 interacting genes: ADAMTSL4 ADNP2 ARL5A ATXN7L2 AURKA AURKB BARD1 CACNB4 CBX1 CBX5 CDC42 DNMT3B DSN1 GDF15 H1-4 H3-4 H3C1 H4C1 HECW2 HIPK2 HTR2C KLF11 L3MBTL1 LAP3 LBR LIG1 MGA MIS12 MKI67 MRPL12 NSD3 PIM1 PRR14 RAD54L2 SP100 STK16 TAF4 TRIM24 TRIM28 VHL ZNF10 ZNF280C ZNF280D ZNF496	42 interacting genes: AR ATN1 ATXN1 ATXN1L BANP BHLHE40 CBX3 FAM118B FXR2 HMG20A HNRNPCL1 HOMER1 IMPDH1 IMPDH2 KIFC3 KRTAP6-3 LCE1D LCE1F NR3C1 NR5A1 NR5A2 PAICS PIAS1 POU1F1 PPARG PSMA3 RBPMS RUNX1T1 RXRA SIAH1 SQSTM1 SUMO1 SUMO2 TAX1BP1 TFAP2D THAP1 TRAF2 TRAF4 UBE2I VCX ZBTB26 ZC2HC1A
Entrez ID		11335	23132
HPRD ID		05130	10018
Ensembl ID		ENSG00000122565	ENSG00000164080
Uniprot IDs		A4D177 Q13185	B3KV54 Q9Y4B4
PDB IDs		2L11 3DM1 3KUP 3TZD 5T1I 6HW2
Enriched GO Terms of Interacting Partners?
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