TMEM106A and ENTPD3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TMEM106A	ENTPD3
Description		transmembrane protein 106A	ectonucleoside triphosphate diphosphohydrolase 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane	Plasma Membrane Membrane Integral Component Of Membrane
	Molecular Function	Molecular_function Protein Binding	Guanosine-diphosphatase Activity Protein Binding ATP Binding Nucleoside-diphosphatase Activity Nucleoside-triphosphatase Activity Uridine-diphosphatase Activity DATP Phosphohydrolase Activity DCTP Phosphohydrolase Activity DUTP Phosphohydrolase Activity DTTP Phosphohydrolase Activity GTP Phosphohydrolase Activity 8-oxo-dGTP Phosphohydrolase Activity DGTP Phosphohydrolase Activity
	Biological Process	Biological_process Positive Regulation Of Interleukin-1 Beta Production Positive Regulation Of Interleukin-6 Production Positive Regulation Of Tumor Necrosis Factor Production CD80 Biosynthetic Process CD86 Biosynthetic Process Macrophage Activation Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of MAPK Cascade Innate Immune Response Positive Regulation Of MHC Class II Biosynthetic Process Positive Regulation Of Nitric Oxide Metabolic Process	Nucleoside Diphosphate Catabolic Process Nucleoside Triphosphate Catabolic Process
Pathways			Phosphate bond hydrolysis by NTPDase proteins
Drugs
Diseases
GWAS		Blood protein levels ( 30072576)	Eosinophil percentage of white cells ( 32888494) Neuroticism ( 29255261)
Interacting Genes		13 interacting genes: ARF1 ENTPD3 ERG28 GJB2 GOSR2 IGFBP5 RHOU TMEM106C TMEM107 TMEM128 TMEM86B TNMD TSPAN4	17 interacting genes: ARL13B CREB3L1 ERGIC3 FAM209A FNDC9 GGT6 GPA33 IFNGR2 LEUTX LHFPL5 LMNA MUC1 PTPN5 RHOA STX2 SYNE4 TMEM106A
Entrez ID		113277	956
HPRD ID		11315	16014
Ensembl ID		ENSG00000184988	ENSG00000168032
Uniprot IDs		B7Z779 Q96A25	O75355
PDB IDs
Enriched GO Terms of Interacting Partners?
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