PARK7 and PINK1

  • Number of citations of the paper that reports this interaction (PubMedID 19229105)
  • 140
  • Data Source:
  • BioGRID (affinity chromatography technology, affinity chromatography technology, pull down)

PARK7

PINK1

Description Parkinsonism associated deglycase PTEN induced kinase 1
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Behcet's disease ( 33393726)
  • Blood protein levels ( 30072576)
  • Celiac disease ( 20190752)
  • Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007)
  • Crohn's disease ( 28067908)
  • Inflammatory bowel disease ( 28067908)
  • Ischemic stroke ( 24262325)
  • Ulcerative colitis ( 28067908 21297633)
  • Household income (MTAG) ( 31844048)
  • Itch intensity from mosquito bite adjusted by bite size ( 28199695)
  • Paclitaxel disposition in epithelial ovarian cancer ( 29367611)
  • Proportion of activated microglia (inferior temporal cortex) ( 30679421)
Interacting Genes 26 interacting genes: BAX BBS1 BCL2L1 CASP8 CSN1S1 DAXX EFCAB6 FADD GOPC GPX4 HIPK1 HSPA5 MAPK8IP1 MAPKAPK5 NDUFA4 PIAS2 PINK1 POLE2 PPP2R1A PPP2R1B PRKACA SNCA SOD1 SUMO1 UBA2 UBE2I 17 interacting genes: APPL2 BAG2 BAG5 BCL2L1 CRLS1 DNM1L FBXO7 HSH2D MAP3K7 MARK2 NEAT1 PARK7 SNCAIP STAT3 TGM2 TRAF6 UBE2M
Entrez ID 11315 65018
HPRD ID 03961 10514
Ensembl ID ENSG00000116288 ENSG00000158828
Uniprot IDs Q99497 V9HWC2 Q9BXM7
PDB IDs 1J42 1P5F 1PDV 1PDW 1PE0 1Q2U 1SOA 1UCF 2OR3 2R1T 2R1U 2R1V 2RK3 2RK4 2RK6 3B36 3B38 3B3A 3BWE 3CY6 3CYF 3CZ9 3CZA 3EZG 3F71 3SF8 4BTE 4MNT 4MTC 4N0M 4N12 4OGF 4OQ4 4P2G 4P34 4P35 4P36 4RKW 4RKY 4S0Z 4ZGG 5IP5 5SY6 5SY9 5SYA 6AF5 6AF7 6AF9 6AFA 6AFB 6AFC 6AFD 6AFE 6AFF 6AFG 6AFH 6AFI 6AFJ 6AFL 6E5Z 6M8Z 7C62
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?