CD300A and TMEM199

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CD300A	TMEM199
Description		CD300a molecule	transmembrane protein 199
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Integral Component Of Membrane Extracellular Exosome Tertiary Granule Membrane Ficolin-1-rich Granule Membrane	Lysosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endomembrane System Integral Component Of Membrane Vacuolar Proton-transporting V-type ATPase Complex COPI-coated Vesicle Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
	Molecular Function	Phosphatidylserine Binding Transmembrane Signaling Receptor Activity Protein Binding Phosphatidylethanolamine Binding Signaling Receptor Activity	Protein Binding
	Biological Process	Immune System Process Cell Adhesion Negative Regulation Of B Cell Proliferation Positive Regulation Of Phosphoprotein Phosphatase Activity Negative Regulation Of Mast Cell Activation Involved In Immune Response Negative Regulation Of MyD88-dependent Toll-like Receptor Signaling Pathway Negative Regulation Of Mast Cell Degranulation Negative Regulation Of MAP Kinase Activity Negative Regulation Of Fibroblast Proliferation Regulation Of T Cell Receptor Signaling Pathway Negative Regulation Of B Cell Receptor Signaling Pathway Negative Regulation Of NK T Cell Activation Negative Regulation Of Phagocytosis, Engulfment Negative Regulation Of Neutrophil Activation Negative Regulation Of Eosinophil Activation Negative Regulation Of Activation Of Janus Kinase Activity Negative Regulation Of Eosinophil Migration	Cellular Iron Ion Homeostasis Lysosomal Lumen Acidification Cellular Response To Increased Oxygen Levels Vacuolar Proton-transporting V-type ATPase Complex Assembly Lysosomal Protein Catabolic Process
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Neutrophil degranulation
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Neurological blood protein biomarker levels ( 31320639)	Apolipoprotein A1 levels ( 32203549) Apolipoprotein B levels ( 32203549) Blood protein levels ( 29875488) HDL cholesterol levels ( 32203549) LDL cholesterol levels ( 32203549) Low density lipoprotein cholesterol levels ( 32154731) Osteoprotegerin levels ( 25080503) Triglyceride levels ( 32203549)
Interacting Genes		7 interacting genes: KRT38 KRTAP10-3 SEC22A SLC9A3R1 TMEM199 TMEM218 TMEM60	17 interacting genes: AQP6 BIK CCR2 CD300A EBP ELOVL4 ERLIN1 IFNGR2 JAGN1 KASH5 LMNA REEP4 SLC10A4 STX1A STX4 TIMMDC1 TMEM14B
Entrez ID		11314	147007
HPRD ID		09492	12679
Ensembl ID		ENSG00000167851	ENSG00000244045
Uniprot IDs		J3QKQ4 Q9UGN4	Q8N511
PDB IDs		2Q87
Enriched GO Terms of Interacting Partners?
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