CHP1 and SLC9A1

Number of citations of the paper that reports this interaction (PubMedID 8901634)
45

Data Source:
HPRD (in vitro, in vivo)

		CHP1	SLC9A1
Description		calcineurin like EF-hand protein 1	solute carrier family 9 member A1
Image
GO Annotations	Cellular Component	Golgi Membrane Nucleus Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum-Golgi Intermediate Compartment Cytosol Plasma Membrane Focal Adhesion Microtubule Cytoskeleton Transport Vesicle Extracellular Exosome	Nucleoplasm Cytoplasm Mitochondrion Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Plasma Membrane Focal Adhesion Cell Surface Intercalated Disc Integral Component Of Membrane Basolateral Plasma Membrane Apical Plasma Membrane Lamellipodium T-tubule Membrane Raft Perinuclear Region Of Cytoplasm Extracellular Exosome Cation-transporting ATPase Complex
	Molecular Function	Protein Kinase Inhibitor Activity Calcium Ion Binding Protein Binding Microtubule Binding Potassium Channel Regulator Activity Kinase Binding Calcium-dependent Protein Binding	Protein Binding Calmodulin Binding Phosphatidylinositol-4,5-bisphosphate Binding Solute:proton Antiporter Activity Sodium:proton Antiporter Activity Potassium:proton Antiporter Activity Protein Phosphatase 2B Binding Protein-macromolecule Adaptor Activity Calcium-dependent Protein Binding Molecular Adaptor Activity Sodium:proton Antiporter Activity Involved In Regulation Of Cardiac Muscle Cell Membrane Potential
	Biological Process	Microtubule Bundle Formation Negative Regulation Of Protein Phosphorylation Negative Regulation Of Protein Kinase Activity Protein Export From Nucleus Potassium Ion Transport Vesicle Targeting Vesicle Fusion Small GTPase Mediated Signal Transduction Negative Regulation Of Phosphatase Activity Membrane Docking Cytoplasmic Microtubule Organization Negative Regulation Of Protein Ubiquitination Negative Regulation Of Protein Autophosphorylation Negative Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of Sodium:proton Antiporter Activity Negative Regulation Of Protein Import Into Nucleus Protein Stabilization Positive Regulation Of Protein Transport Protein Complex Oligomerization Regulation Of Intracellular PH Positive Regulation Of Protein Glycosylation Membrane Organization Membrane Fusion Negative Regulation Of Calcineurin-NFAT Signaling Cascade Positive Regulation Of Phospholipid Biosynthetic Process Cellular Response To Acidic PH Positive Regulation Of Protein Targeting To Membrane Regulation Of Neuron Death	Ion Transport Cellular Sodium Ion Homeostasis Regulation Of PH Response To Acidic PH Positive Regulation Of Cardiac Muscle Hypertrophy Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Cell Migration Maintenance Of Cell Polarity Positive Regulation Of Cell Growth Cellular Response To Insulin Stimulus Positive Regulation Of Mitochondrial Membrane Permeability Response To Muscle Stretch Sodium Ion Export Across Plasma Membrane Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Positive Regulation Of Action Potential Positive Regulation Of Transcription By RNA Polymerase II Protein Complex Oligomerization Regulation Of Intracellular PH Regulation Of Stress Fiber Assembly Regulation Of Focal Adhesion Assembly Regulation Of Sensory Perception Of Pain Cardiac Muscle Cell Differentiation Cellular Response To Cold Positive Regulation Of Calcineurin-NFAT Signaling Cascade Neuron Death Cellular Response To Antibiotic Cellular Response To Electrical Stimulus Cellular Response To Mechanical Stimulus Cellular Response To Hypoxia Cellular Response To Acidic PH Potassium Ion Transmembrane Transport Cellular Response To Epinephrine Stimulus Cardiac Muscle Cell Contraction Regulation Of Cardiac Muscle Cell Membrane Potential Regulation Of The Force Of Heart Contraction By Cardiac Conduction Anion Transmembrane Transport Sodium Ion Import Across Plasma Membrane Positive Regulation Of The Force Of Heart Contraction Proton Transmembrane Transport Positive Regulation Of Calcium:sodium Antiporter Activity
Pathways		Hyaluronan uptake and degradation	Hyaluronan uptake and degradation Sodium/Proton exchangers
Drugs		Calcium citrate Calcium Phosphate Calcium phosphate dihydrate	Amiloride Homoserine Lactone Cariporide
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29785011) Essential hypertension (time to event) ( 32589924) Estimated glomerular filtration rate ( 31015462) Ulcerative colitis ( 28067908) White blood cell count ( 32888494)	Lateral ventricle volume ( 31530798)
Interacting Genes		10 interacting genes: GAPDH KIF1B PRSS23 SLC9A1 SLC9A2 SLC9A3 SLC9A4 SLC9A5 STK17B UBC	15 interacting genes: CA2 CHP1 CHP2 DAXX MAP3K14 MAP4K4 MAPK1 MAPK14 MDFI MTOR SDHB SLC45A1 TESC WNK1 YWHAB
Entrez ID		11261	6548
HPRD ID		06101	00123
Ensembl ID		ENSG00000187446	ENSG00000090020
Uniprot IDs		A0A024R9M9 H0YKE7 Q99653	B2RAH2 P19634
PDB IDs		2E30	1Y4E 2BEC 2E30 2HTG 2KBV 2L0E 2MDF 2YGG 6BJF 6NUC 6NUF 6NUU
Enriched GO Terms of Interacting Partners?
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