PDCD10 and STK26

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid, biochemical, affinity chromatography technology, two hybrid, affinity chromatography technology)

		PDCD10	STK26
Description		programmed cell death 10	serine/threonine kinase 26
Image
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Golgi Apparatus Cytosol Plasma Membrane Extracellular Exosome FAR/SIN/STRIPAK Complex	Golgi Membrane Cytoplasm Golgi Apparatus Golgi-associated Vesicle Cytosol Vesicle Membrane Membrane Apical Plasma Membrane Perinuclear Region Of Cytoplasm Extracellular Exosome Cell Periphery
	Molecular Function	Protein Binding Protein Kinase Binding Protein Homodimerization Activity Protein N-terminus Binding	Magnesium Ion Binding Protein Kinase Activity Protein Binding ATP Binding Identical Protein Binding Protein Homodimerization Activity Protein Serine Kinase Activity
	Biological Process	Angiogenesis Positive Regulation Of Cell Population Proliferation Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Positive Regulation Of Cell Migration Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Peptidyl-serine Phosphorylation Regulation Of Rho Protein Signal Transduction Intrinsic Apoptotic Signaling Pathway In Response To Hydrogen Peroxide Response To Hydrogen Peroxide Negative Regulation Of Apoptotic Process Stress Fiber Assembly Positive Regulation Of MAP Kinase Activity Wound Healing, Spreading Of Cells Positive Regulation Of Notch Signaling Pathway Protein Stabilization Establishment Of Golgi Localization Positive Regulation Of Protein Serine/threonine Kinase Activity Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Golgi Reassembly Positive Regulation Of Intracellular Protein Transport Regulation Of Golgi Organization Negative Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Cellular Response To Leukemia Inhibitory Factor	Protein Phosphorylation Apoptotic Process Cellular Response To Starvation Microvillus Assembly Negative Regulation Of Cell Migration Response To Hydrogen Peroxide Regulation Of Apoptotic Process Protein Autophosphorylation Regulation Of Hydrogen Peroxide-induced Cell Death
Pathways			Apoptotic cleavage of cellular proteins
Drugs			2-[4-[4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]quinazolin-2-yl]iminocyclohexa-2,5-dien-1-yl]acetonitrile Fostamatinib
Diseases
GWAS		Fast beta electroencephalogram ( 28070124) Platelet count ( 32888494)	Gestational age at birth (maternal effect) ( 28877031)
Interacting Genes		13 interacting genes: C4orf19 CHMP5 FAM118B FARSA FRYL MINAR1 PLEKHS1 PROSER2 RHOA STK24 STK25 STK26 STRN	13 interacting genes: APP CEP76 GOLGA2 GRB14 IKZF3 MBP NEDD4 OGT PDCD10 RAF1 SRPK1 TRAF6 TRIM27
Entrez ID		11235	51765
HPRD ID		10141	06663
Ensembl ID		ENSG00000114209	ENSG00000134602
Uniprot IDs		C9J363 Q9BUL8	Q9P289
PDB IDs		3AJM 3L8I 3L8J 3RQE 3RQF 3RQG 3W8H 3W8I 4GEH 4TVQ	3GGF 3W8I 4FZA 4FZD 4FZF 4GEH 5XY9 5YF4 7B36
Enriched GO Terms of Interacting Partners?
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