DDX20 and STXBP3

Number of citations of the paper that reports this interaction (PubMedID 12065586)
43

Data Source:
HPRD (in vivo)

		DDX20	STXBP3
Description		DEAD-box helicase 20	syntaxin binding protein 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Cytoskeleton Membrane SMN Complex SMN-Sm Protein Complex RNA Polymerase II Transcription Repressor Complex Gemini Of Coiled Bodies	Cytosol Plasma Membrane Basolateral Plasma Membrane Apical Plasma Membrane Secretory Granule Platelet Alpha Granule Specific Granule Phagocytic Vesicle Extracellular Exosome Tertiary Granule Presynapse
	Molecular Function	DNA Binding RNA Binding RNA Helicase Activity Protein Binding ATP Binding ATP Hydrolysis Activity Protein Domain Specific Binding Protein-macromolecule Adaptor Activity Histone Deacetylase Binding DNA-binding Transcription Factor Binding	Protein Binding Syntaxin-1 Binding Syntaxin Binding Protein-containing Complex Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Spliceosomal Tri-snRNP Complex Assembly Spliceosomal SnRNP Assembly RNA Processing Negative Regulation Of Cell Population Proliferation Positive Regulation Of Apoptotic Process Oogenesis Regulation Of Steroid Biosynthetic Process	Cellular Glucose Homeostasis Intracellular Protein Transport Vesicle Docking Involved In Exocytosis Neurotransmitter Secretion Brain Development Vesicle-mediated Transport Protein To Membrane Docking Insulin Secretion Response To Insulin Neutrophil Degranulation Negative Regulation Of Calcium Ion-dependent Exocytosis Negative Regulation Of Glucose Import Platelet Aggregation Cellular Response To Interferon-gamma
Pathways		snRNP Assembly	Disinhibition of SNARE formation Translocation of SLC2A4 (GLUT4) to the plasma membrane
Drugs
Diseases
GWAS		Body mass index ( 29273807) Metabolite levels ( 23823483) Venous thromboembolism ( 32232851)	Fat distribution (HIV) ( 21897333)
Interacting Genes		32 interacting genes: AGO2 APP CRYAB DHX9 ETV3 GEMIN2 GEMIN4 GEMIN5 HDAC2 HDAC5 NCOR1 NCOR2 NR0B2 NUFIP1 PRRC2A RN7SL1 RNU1-1 RNU2-1 SIN3A SMN1 SMN2 SNRPB SNRPD1 SNRPD2 SNRPD3 SNRPE SNRPF SNRPG SNUPN STXBP2 STXBP3 TP53	14 interacting genes: DDX20 GEMIN2 GEMIN4 GEMIN5 PRKCA RPL3 SMN1 SNRPB SNRPD2 SNRPD3 SNTG1 STX4 STXBP2 VAMP2
Entrez ID		11218	6814
HPRD ID		05859	10517
Ensembl ID		ENSG00000064703	ENSG00000116266
Uniprot IDs		Q9H4N4 Q9UHI6	O00186
PDB IDs		2OXC 3B7G
Enriched GO Terms of Interacting Partners?
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