CHM and RAB18

Number of citations of the paper that reports this interaction (PubMedID 12535645)
5

Data Source:
HPRD (two hybrid)

		CHM	RAB18
Description		CHM Rab escort protein	RAB18, member RAS oncogene family
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Rab-protein Geranylgeranyltransferase Complex	Endoplasmic Reticulum Membrane Golgi Apparatus Lipid Droplet Cytosol Plasma Membrane Endomembrane System Apical Plasma Membrane Secretory Granule Membrane Synapse Endoplasmic Reticulum Tubular Network
	Molecular Function	Rab Geranylgeranyltransferase Activity GDP-dissociation Inhibitor Activity GTPase Activator Activity Protein Binding Small GTPase Binding	GTPase Activity Protein Binding GTP Binding GDP Binding
	Biological Process	Protein Targeting To Membrane Small GTPase Mediated Signal Transduction Visual Perception Vesicle-mediated Transport Protein Geranylgeranylation Regulation Of Catalytic Activity	Eye Development Intracellular Protein Transport Small GTPase Mediated Signal Transduction Brain Development Lipid Droplet Organization Endoplasmic Reticulum Tubular Network Organization
Pathways		TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs	Neutrophil degranulation COPI-independent Golgi-to-ER retrograde traffic RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Metabolite levels ( 23823483) Pit-and-Fissure caries ( 24556642) Smooth-surface caries ( 24556642)	Benign childhood epilepsy with centro-temporal spikes ( 32580138) Body shape index ( 34021172) Childhood ear infection ( 27182965 28928442) Diisocyanate-induced asthma ( 25918132) Heel bone mineral density ( 30598549 28869591) Height ( 31562340) Hip circumference adjusted for BMI ( 28552196) Refractive error ( 32231278) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		11 interacting genes: RAB14 RAB18 RAB1B RAB32 RAB3A RAB3B RAB3D RAB4A RAB5B RAB6A RAB7A	15 interacting genes: APBB1IP AQP6 CHM DVL3 ELOVL4 ERRFI1 FAM107A PDE6D PPP2R1A PPP2R1B PRTFDC1 TAX1BP1 TOM1L1 TREH UCN
Entrez ID		1121	22931
HPRD ID		02312	03731
Ensembl ID		ENSG00000188419	ENSG00000099246
Uniprot IDs		A8K545 B4DRL9 P24386	A0A087X163 B7Z4P9 B7Z5V3 Q9NP72
PDB IDs			1X3S
Enriched GO Terms of Interacting Partners?
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