CHKA and FCHSD2

Number of citations of the paper that reports this interaction (PubMedID 18654987)
21

Data Source:
BioGRID (two hybrid)

		CHKA	FCHSD2
Description		choline kinase alpha	FCH and double SH3 domains 2
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GO Annotations	Cellular Component	Cytoplasm Cytosol	Plasma Membrane Clathrin-coated Pit Neuromuscular Junction Recycling Endosome Stereocilium Shaft
	Molecular Function	Choline Kinase Activity Cholinesterase Activity Ethanolamine Kinase Activity ATP Binding Choline Binding Identical Protein Binding	Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Phosphatidylinositol-3,4-bisphosphate Binding
	Biological Process	Ethanolamine Metabolic Process Lipid Metabolic Process Phosphatidylethanolamine Biosynthetic Process Phosphatidylcholine Biosynthetic Process CDP-choline Pathway Lipid Transport Response To Toxic Substance Phosphorylation Choline Metabolic Process Response To 3-methylcholanthrene	Neuromuscular Synaptic Transmission Protein Transport Regulation Of Actin Filament Polymerization Positive Regulation Of Actin Filament Polymerization Multi-organism Membrane Organization Clathrin-dependent Endocytosis Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation
Pathways		Synthesis of PC Synthesis of PE
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 33730874)	Albumin-globulin ratio ( 29403010) Crohn's disease ( 23850713 23266558) Endometrial cancer (endometrioid histology) ( 30093612) Health literacy ( 31250787) Nicotine dependence symptom count ( 25555482) Serum total protein level ( 29403010) Systemic lupus erythematosus ( 33272962 26663301)
Interacting Genes		6 interacting genes: APP DEPTOR FCHSD2 PSEN2 RCC1 SKP2	53 interacting genes: ABCF3 ACAP1 ANKS1A ATPAF2 BORCS6 C2orf73 C9orf78 CASK CCDC120 CCDC158 CCDC183 CCDC85B CCT2 CFAP36 CHKA CTAG1A CTAG1B DAPP1 ENKD1 FAM9B GPRASP2 HDAC4 HGS HOMER1 HSP90AB1 HSPA5 HTRA1 ITSN1 ITSN2 KIFC3 LCA5L LDOC1 MNS1 MRFAP1 MSL1 MTUS2 PDE2A PDE4DIP PRKAR1B RINT1 SASS6 SERTAD3 SH2D4A SH3BGR SRP72 TLE5 TSGA10IP USHBP1 VCPIP1 VPS37C WAS WASL ZNF587
Entrez ID		1119	9873
HPRD ID		00327	13321
Ensembl ID		ENSG00000110721	ENSG00000137478
Uniprot IDs		P35790	O94868
PDB IDs		2CKO 2CKP 2CKQ 2I7Q 3F2R 3G15 3ZM9 4BR3 4CG8 4CG9 4CGA 4DA5 5AFV 5EQE 5EQP 5EQY 5FTG 5FUT 5W6O 7A04 7A06	2DL5 2DL7 6GBU
Enriched GO Terms of Interacting Partners?
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