IL1RAPL1 and ARHGAP22

Number of citations of the paper that reports this interaction (PubMedID 21926414)
44

Data Source:
BioGRID (pull down)

		IL1RAPL1	ARHGAP22
Description		interleukin 1 receptor accessory protein like 1	Rho GTPase activating protein 22
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Cell Surface Integral Component Of Membrane Axon Dendrite Postsynaptic Membrane Glutamatergic Synapse	Nucleus Cytosol Focal Adhesion Glutamatergic Synapse
	Molecular Function	Signaling Receptor Binding Protein Binding Interleukin-1 Binding NAD(P)+ Nucleosidase Activity NAD+ Nucleotidase, Cyclic ADP-ribose Generating	GTPase Activator Activity Protein Binding
	Biological Process	Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Signal Transduction Regulation Of Neuron Projection Development Neuron Differentiation Negative Regulation Of Exocytosis Positive Regulation Of Dendrite Morphogenesis Positive Regulation Of Synapse Assembly Presynaptic Membrane Assembly Regulation Of Postsynapse Organization Trans-synaptic Signaling By Trans-synaptic Complex Regulation Of Presynapse Assembly	Angiogenesis Signal Transduction Cell Differentiation Regulation Of Small GTPase Mediated Signal Transduction Activation Of GTPase Activity Regulation Of Postsynapse Organization
Pathways		Receptor-type tyrosine-protein phosphatases Interleukin-38 signaling	RHOA GTPase cycle CDC42 GTPase cycle RAC1 GTPase cycle
Drugs
Diseases
GWAS		Cardiovascular risk factors (age interaction) ( 20838585) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Vitiligo ( 27723757)	Conduct disorder ( 20585324) Daytime sleep phenotypes ( 27126917) Diabetic retinopathy ( 21310492) Macular thickness ( 30535121) Refractive error ( 32231278) Self-employment ( 23593239) Systolic blood pressure ( 31134134) Systolic blood pressure (education interaction) ( 31134134)
Interacting Genes		3 interacting genes: ARHGAP22 NCS1 POLA1	13 interacting genes: ALG11 CACNA1A CCNDBP1 CDC42 DEF6 FXR1 GPRIN2 IL1RAPL1 MAPK8 PTPN20 RAC1 RHOA ZNF488
Entrez ID		11141	58504
HPRD ID		02193	12476
Ensembl ID		ENSG00000169306	ENSG00000128805
Uniprot IDs		Q9NZN1 X5DNQ7	A0A2X0SFC0 Q7Z5H3
PDB IDs		1T3G 4M92 5WY8
Enriched GO Terms of Interacting Partners?
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