PRDM4 and SERTAD1

Number of citations of the paper that reports this interaction (PubMedID 20211142)
361

Data Source:
BioGRID (two hybrid)

		PRDM4	SERTAD1
Description		PR/SET domain 4	SERTA domain containing 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Histone Methyltransferase Complex	Nucleus Cytoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Methyltransferase Activity Metal Ion Binding Histone Methyltransferase Binding Sequence-specific Double-stranded DNA Binding	Protein Binding Transcription Regulator Activity
	Biological Process	Transcription By RNA Polymerase II Regulation Of Gene Expression Histone H4-R3 Methylation Positive Regulation Of Transcription By RNA Polymerase II	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Positive Regulation Of Cell Population Proliferation Positive Regulation Of Transcription By RNA Polymerase II Chromatin-mediated Maintenance Of Transcription
Pathways		p75NTR negatively regulates cell cycle via SC1
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Daytime nap ( 33568662) Sleep duration ( 30846698)	Monocyte percentage of white cells ( 32888494) Otitis media ( 27632927) Otitis media (chronic) ( 27632927) Otitis media (recurrent) ( 27632927)
Interacting Genes		9 interacting genes: CTNNBL1 DAO EIF4E EMX1 MSRB3 NCS1 SERTAD1 SMAD3 UNG	57 interacting genes: ADCY1 ASB8 ATG12 ATXN7L3 BANF2 C1orf109 CCND2 CDK4 CDKN2A CHAF1A CHURC1 CIB3 CINP CKS1B COPB1 CREBBP DENND4A EGLN3 ELOC EP300 FAAP20 FAH FNDC11 FXR1 GLYCTK HIVEP1 HSPB1 KAT2B KLC4 KLHL42 MVP NEDD4 P4HA3 PATE1 PBX4 PICK1 PIH1D2 POT1 PRDM4 PSORS1C2 RBX1 RCHY1 ROPN1 SEC14L4 SETD7 SFI1 SMAD3 SPEN SSX7 STAT5B SUPT7L TGM2 TLR4 TRIM28 TSC1 XIAP ZNF410
Entrez ID		11108	29950
HPRD ID		10425	15326
Ensembl ID		ENSG00000110851	ENSG00000197019
Uniprot IDs		A0A024RBM7 B3KPI0 Q9UKN5	Q53GC0 Q9UHV2
PDB IDs		2L9Z 3DB5
Enriched GO Terms of Interacting Partners?
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