PRDM5 and FAAP20

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PRDM5	FAAP20
Description		PR/SET domain 5	FA core complex associated protein 20
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Nuclear Body	Nucleoplasm Chromosome Nuclear Body Cell Junction Fanconi Anaemia Nuclear Complex
	Molecular Function	Transcription Cis-regulatory Region Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Methyltransferase Activity Sequence-specific DNA Binding Metal Ion Binding DNA-binding Transcription Factor Binding	Protein Binding Polyubiquitin Modification-dependent Protein Binding Ubiquitin Binding Metal Ion Binding K63-linked Polyubiquitin Modification-dependent Protein Binding Ubiquitin-dependent Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Mitotic Cell Cycle Regulation Of Gene Expression Histone Deacetylation Negative Regulation Of Transcription, DNA-templated Histone H3-K9 Methylation Cellular Response To Leukemia Inhibitory Factor	Cellular Response To DNA Damage Stimulus Translesion Synthesis Interstrand Cross-link Repair
Pathways			Fanconi Anemia Pathway
Drugs
Diseases
GWAS		F-cell distribution in sickle cell anaemia ( 21326311) Fasting plasma glucose ( 17903298) Hemoglobin levels ( 33491795) Loneliness (multivariate analysis) ( 27629369) Monobrow thickness ( 26926045) Obesity-related traits ( 23251661) Schizophrenia, bipolar disorder or recurrent major depressive disorder ( 34099189) Sensorimotor dexterity ( 31596458)	Sedentary behaviour duration ( 30531941) TPE interval (resting) ( 32386560)
Interacting Genes		7 interacting genes: ADPRS CLCN1 FAAP20 FBXO44 RASD1 TYK2 VIPR1	28 interacting genes: ARNT2 BPIFA1 CRX CT55 CTDSP1 DDIT4L DUSP21 FANCF GOLGA6L9 INCA1 KRTAP6-2 KRTAP8-1 LCN2 LMO2 LRP2BP MEOX2 MOB2 NFKBID PFDN5 PIN1 PRDM5 REL REV1 SERTAD1 SERTAD3 TEX11 TRIB3 UBC
Entrez ID		11107	199990
HPRD ID		17902	08707
Ensembl ID		ENSG00000138738	ENSG00000162585
Uniprot IDs		Q9NQX1	A0A024R0B3 Q6NZ36 Q6ZRT9 Q7Z4P6
PDB IDs			2MUQ 2MUR 3WWQ
Enriched GO Terms of Interacting Partners?
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