HNRNPUL1 and RPA2

Number of citations of the paper that reports this interaction (PubMedID 24332808)
105

Data Source:
BioGRID (pull down, affinity chromatography technology)

		HNRNPUL1	RPA2
Description		heterogeneous nuclear ribonucleoprotein U like 1	replication protein A2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Chromosome, Telomeric Region Chromatin Nucleus Nucleoplasm DNA Replication Factor A Complex Nuclear Body PML Body Site Of Double-strand Break
	Molecular Function	RNA Binding Protein Binding Enzyme Binding	Damaged DNA Binding Single-stranded DNA Binding Protein Binding Enzyme Binding Protein Phosphatase Binding Ubiquitin Protein Ligase Binding Protein N-terminus Binding G-rich Strand Telomeric DNA Binding
	Biological Process	RNA Processing Response To Virus	Telomere Maintenance Double-strand Break Repair Via Homologous Recombination DNA Replication Base-excision Repair Nucleotide-excision Repair Mismatch Repair Regulation Of Double-strand Break Repair Via Homologous Recombination Mitotic G1 DNA Damage Checkpoint Signaling Protein Localization To Chromosome Regulation Of DNA Damage Checkpoint
Pathways		mRNA Splicing - Major Pathway	Translesion synthesis by REV1 Recognition of DNA damage by PCNA-containing replication complex Translesion Synthesis by POLH Removal of the Flap Intermediate from the C-strand Activation of ATR in response to replication stress Regulation of HSF1-mediated heat shock response HSF1 activation Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) PCNA-Dependent Long Patch Base Excision Repair Translesion synthesis by POLK Translesion synthesis by POLI Termination of translesion DNA synthesis HDR through Single Strand Annealing (SSA) HDR through Homologous Recombination (HRR) Processing of DNA double-strand break ends Presynaptic phase of homologous DNA pairing and strand exchange Formation of Incision Complex in GG-NER Gap-filling DNA repair synthesis and ligation in GG-NER Dual Incision in GG-NER Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER Fanconi Anemia Pathway Regulation of TP53 Activity through Phosphorylation Activation of the pre-replicative complex Removal of the Flap Intermediate G2/M DNA damage checkpoint Meiotic recombination
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) HDL cholesterol levels ( 32203549) Heel bone mineral density ( 28869591) Urinary albumin-to-creatinine ratio ( 31511532)	HDL cholesterol levels ( 32203549) Platelet count ( 32888494) Plateletcrit ( 32888494) White blood cell count ( 32888494)
Interacting Genes		52 interacting genes: BRD7 CRMP1 DMRTB1 DZIP3 EP300 ERG ERG28 EWSR1 FXR1 GIT2 HNRNPF HNRNPH2 HNRNPH3 IL7R ITCH KLHDC7B MAPK1IP1L MARS1 MED31 NEDD4 NXF1 NXF2 NXF3 PIAS2 PIAS4 PPIL1 PPP1R13B PRMT1 PRMT2 PRPF40A PTEN RBM22 RBM4 RBM4B ROPN1 RPA1 RPA2 SF1 SF3B4 SMN1 SMN2 SNRPB2 SNRPC SORBS3 SRSF9 TGM2 TLX3 TP53 TP53BP2 VPS37C WWP2 ZNF207	65 interacting genes: ACP5 AKAP9 APP ATM CALCOCO2 CASK CCNC CCNO CDC5L CDK1 CEP126 CFB COPS6 CRMP1 DMRTB1 EEF1A1 EIF4G2 ERCC1 ERCC4 GAPDH GOLM1 HERPUD1 HNRNPUL1 HUS1 LNX2 LRIF1 MARK2 MCM2 MCM5 MED1 MED31 MEN1 NDEL1 ORC1 ORC2 ORC4 ORC5 PCM1 PIAS1 PIAS4 PPP4C PRC1 PRKCI PRKDC RAD1 RAD51 RAD52 RAD9A RBM14 RBM48 RPA1 RPA3 RPLP1 SDF4 SERTAD3 SLC17A9 STAT3 TLE1 TUBB2A UNC119 UNG UTP14A XPA YWHAE ZBTB14
Entrez ID		11100	6118
HPRD ID		10428	01566
Ensembl ID		ENSG00000105323	ENSG00000117748
Uniprot IDs		A0A024R0J9 A0A0A0MRA5 A8K3W4 B7Z4B8 Q9BUJ2	B4DUL2 P15927
PDB IDs			1DPU 1L1O 1QUQ 1Z1D 2PI2 2PQA 2Z6K 3KDF 4MQV 4OU0
Enriched GO Terms of Interacting Partners?
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