PRSS23 and TRAPPC4

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PRSS23	TRAPPC4
Description		serine protease 23	trafficking protein particle complex subunit 4
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Endoplasmic Reticulum Lumen Extracellular Exosome	Golgi Membrane Endoplasmic Reticulum Golgi Stack Cytosol Synaptic Vesicle TRAPP Complex Dendrite Synapse Postsynaptic Membrane
	Molecular Function	Serine-type Endopeptidase Activity Protein Binding	Protein Binding
	Biological Process	Proteolysis	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Autophagy Dendrite Development
Pathways		Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation	COPII-mediated vesicle transport Syndecan interactions RAB GEFs exchange GTP for GDP on RABs
Drugs			S-palmitoyl-L-cysteine
Diseases
GWAS		Blood urea nitrogen levels ( 31152163) Chronic obstructive pulmonary disease ( 30804561) FEV1 ( 30804560) Heel bone mineral density ( 30598549 28869591) Intraocular pressure ( 29617998 29785010) Lung function (FEV1) ( 28166213) Lung function (FEV1/FVC) ( 30804560) Peak expiratory flow ( 30804560)
Interacting Genes		26 interacting genes: ACTG1 APP B2M CHP1 EFNA3 FXR1 GATD1 GRK6 HSPA4 MAPK8IP2 NCAPD3 NIPBL NOC4L ODF2L PDPK1 PHF23 PPIA RACGAP1 RECQL4 RPL4P5 SEC11C SHMT1 SLC25A6 TCF12 TMEM222 TRAPPC4	10 interacting genes: APP PRSS23 SDC2 TFIP11 TRAPPC11 TRAPPC12 TRAPPC2 TRAPPC2L TRAPPC3L TRAPPC8
Entrez ID		11098	51399
HPRD ID		07149	18220
Ensembl ID		ENSG00000150687	ENSG00000196655
Uniprot IDs		O95084	B4DF86 E9PKS9 E9PQE8 J3KP27 Q9Y296
PDB IDs			2J3T 2JSN 2ZMV
Enriched GO Terms of Interacting Partners?
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