RER1 and WIPF1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		RER1	WIPF1
Description		retention in endoplasmic reticulum sorting receptor 1	WAS/WASL interacting protein family member 1
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Plasma Membrane Cell Surface Integral Component Of Golgi Membrane	Ruffle Cytosol Actin Filament Actin Cytoskeleton Cytoplasmic Vesicle
	Molecular Function	Molecular_function Protein Binding Acetylcholine Receptor Binding	Actin Binding Protein Binding Profilin Binding SH3 Domain Binding
	Biological Process	Protein Retention In ER Lumen Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Skeletal Muscle Acetylcholine-gated Channel Clustering Positive Regulation Of Protein Localization To Plasma Membrane	Actin Polymerization Or Depolymerization Actin Filament-based Movement Protein-containing Complex Assembly
Pathways			Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs CDC42 GTPase cycle RAC1 GTPase cycle FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis
Drugs
Diseases
GWAS		Body mass index ( 26426971) Metabolite levels ( 23823483) Serum alkaline phosphatase levels ( 33547301) Vitamin C levels ( 33203707)	Atrial fibrillation ( 30061737 29892015) Mean platelet volume ( 32888494) Platelet distribution width ( 32888494) Pulse pressure ( 27841878) Resting heart rate ( 27798624) Systolic blood pressure ( 27841878) Urate levels (BMI interaction) ( 25811787)
Interacting Genes		7 interacting genes: GCH1 HAP1 IMMT SCAND1 SH3GL3 SYT16 WIPF1	27 interacting genes: ABI2 ACTC1 ACTG1 ALAS1 APBB1 CACNG2 CDC42 CRKL CTTN FASTK GRB2 HCK HLCS HOMER3 ITSN2 NCK1 NCK2 PRKCQ PRPF40A RER1 SEC24C SH3RF1 WAS WASL WBP4 WWP2 ZAP70
Entrez ID		11079	7456
HPRD ID		17967	03835
Ensembl ID		ENSG00000157916	ENSG00000115935
Uniprot IDs		O15258 Q5T094	A0A140VJZ9 O43516 Q2YDC4
PDB IDs			2A41
Enriched GO Terms of Interacting Partners?
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