TPPP and CDK11B

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		TPPP	CDK11B
Description		tubulin polymerization promoting protein	cyclin dependent kinase 11B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Cytosol Microtubule Perinuclear Region Of Cytoplasm Mitotic Spindle Microtubule Bundle Postsynaptic Golgi Apparatus	Nucleus Cytoplasm
	Molecular Function	Magnesium Ion Binding GTPase Activity Protein Binding Microtubule Binding Tubulin Binding Protein Homodimerization Activity	RNA Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Cyclin-dependent Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity
	Biological Process	Microtubule Bundle Formation Oligodendrocyte Development Astral Microtubule Organization Positive Regulation Of Protein-containing Complex Assembly Positive Regulation Of Myelination Positive Regulation Of Protein Polymerization Myelin Assembly Microtubule Polymerization Oligodendrocyte Differentiation Cell Division Microtubule Nucleation By Microtubule Organizing Center Regulation Of Microtubule Cytoskeleton Organization Negative Regulation Of Tubulin Deacetylation	Mitotic Cell Cycle Regulation Of Cell Growth Regulation Of Transcription, DNA-templated Protein Phosphorylation Apoptotic Process Regulation Of Mitotic Cell Cycle Regulation Of MRNA Processing
Pathways			Recruitment of mitotic centrosome proteins and complexes
Drugs
Diseases
GWAS		Barrett's esophagus or Esophageal adenocarcinoma ( 27527254) Esophageal adenocarcinoma ( 27527254) Estimated glomerular filtration rate ( 31152163) Estimated glomerular filtration rate in diabetes ( 31451708) Estimated glomerular filtration rate in non-diabetics ( 31451708) Haemorrhoidal disease ( 33888516) Idiopathic downbeat nystagmus ( 32157568) Ulcerative colitis ( 28067908 20228799)	Body mass index ( 26426971)
Interacting Genes		10 interacting genes: APP CDK11B DYNLL2 GAPDH GSK3B HDAC6 ROCK1 SNCA TUBB ZNF114	24 interacting genes: AP2M1 CASP1 CASP3 CASP8 CCND3 CCNL2 CHEK2 EIF3F KAT7 MSN PAK1 PIN1 PPIL3 RANBP9 RPS27A TCEA2 TH TPPP URM1 YWHAB YWHAE YWHAG YWHAQ YWHAZ
Entrez ID		11076	984
HPRD ID		18522	08909
Ensembl ID		ENSG00000171368	ENSG00000248333
Uniprot IDs		O94811 Q4L233	B4DII1 P21127
PDB IDs
Enriched GO Terms of Interacting Partners?
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