TMEM115 and HTATIP2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TMEM115	HTATIP2
Description		transmembrane protein 115	HIV-1 Tat interactive protein 2
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Nucleus Golgi Apparatus Integral Component Of Membrane Golgi Cisterna Membrane	Nucleus Nuclear Envelope Cytoplasm Cytosol Membrane
	Molecular Function	Molecular_function Protein Binding Identical Protein Binding	Transcription Coactivator Activity Protein Serine/threonine Kinase Activity Protein Binding Oxidoreductase Activity
	Biological Process	Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Negative Regulation Of Cell Population Proliferation Protein Transport	Angiogenesis Regulation Of Transcription By RNA Polymerase II Apoptotic Process Cell Differentiation Negative Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Regulation Of Angiogenesis Positive Regulation Of Transcription By RNA Polymerase II Protein Autophosphorylation Import Into Nucleus
Pathways		COPI-mediated anterograde transport
Drugs			Polyethylene glycol 400
Diseases
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Sleep duration (short sleep) ( 30846698) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Bell's palsy ( 33602968) Fractional shortening ( 29403010) Obesity-related traits ( 23251661) Response to inhaled glucocorticoid treatment in asthma (change in FEV1) ( 25601762)
Interacting Genes		13 interacting genes: AQP6 ASPG CREB3 CYB5R3 HTATIP2 MANBAL RABAC1 RASSF1 SYNE4 TLCD4 TMED8 TMX2 ZDHHC17	25 interacting genes: ABHD4 ACSL4 AQP6 ASF1A EHHADH ETS1 FAM209A FITM2 GET1 HDAC6 HSD17B11 JAGN1 JPH1 MIEF1 MTIF3 NCOA5 PITPNC1 PLIN2 RAB5A REEP4 RETREG3 SH3GLB1 SLC10A6 TMEM115 TMX2
Entrez ID		11070	10553
HPRD ID		06144	09288
Ensembl ID		ENSG00000126062	ENSG00000109854
Uniprot IDs		A0A024R2Y2 Q12893	Q9BUP3
PDB IDs			2BKA
Enriched GO Terms of Interacting Partners?
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