SLC27A2 and ICOSLG

		SLC27A2	ICOSLG
Description		solute carrier family 27 member 2	inducible T cell costimulator ligand
Image		No pdb structure
GO Annotations	Cellular Component	Peroxisomal Membrane Integral Component Of Peroxisomal Membrane Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Integral Component Of Endoplasmic Reticulum Membrane Specific Granule Membrane Extracellular Exosome	Plasma Membrane External Side Of Plasma Membrane Integral Component Of Membrane Cytoplasmic Ribonucleoprotein Granule Extracellular Exosome
	Molecular Function	Long-chain Fatty Acid-CoA Ligase Activity Long-chain Fatty Acid Transporter Activity ATP Binding Fatty Acid Transmembrane Transporter Activity Enzyme Binding Very Long-chain Fatty Acid-CoA Ligase Activity Arachidonate-CoA Ligase Activity Cholate-CoA Ligase Activity Phytanate-CoA Ligase Activity Pristanate-CoA Ligase Activity	Signaling Receptor Binding Protein Binding Identical Protein Binding
	Biological Process	Fatty Acid Alpha-oxidation Long-chain Fatty Acid Metabolic Process Fatty Acid Beta-oxidation Bile Acid Biosynthetic Process Very Long-chain Fatty Acid Catabolic Process Long-chain Fatty Acid Import Into Cell Methyl-branched Fatty Acid Metabolic Process	Regulation Of Cytokine Production Adaptive Immune Response Defense Response Hyperosmotic Response Signal Transduction Positive Regulation Of Activated T Cell Proliferation T Cell Activation B Cell Activation T Cell Receptor Signaling Pathway
Pathways		Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol Synthesis of bile acids and bile salts via 24-hydroxycholesterol Alpha-oxidation of phytanate Neutrophil degranulation Peroxisomal protein import Peroxisomal protein import	Costimulation by the CD28 family
Drugs
Diseases
GWAS		Blood metabolite ratios ( 24816252) Platelet count ( 32888494) Verbal declarative memory ( 25648963)	Ankylosing spondylitis ( 23749187) Blood protein levels ( 30072576 29875488) Celiac disease ( 22057235 20190752) Cerebral amyloid deposition (PET imaging) ( 30361487) Crohn's disease ( 18587394 21102463) Eosinophil counts ( 32888494 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 32888494 27863252) Inflammatory bowel disease ( 23128233) Left ventricular QRS voltage ( 27195777) Rheumatoid arthritis ( 30423114) Type 1 diabetes ( 25751624 34127860) Ulcerative colitis ( 21297633)
Interacting Genes		17 interacting genes: ABCD1 AP4E1 ARPP19 DTWD1 FAM214A GABPB1 GEMIN5 ICOSLG LGI1 PDCD11 PDE6G PEX5 PML RAB5C SLC24A1 UBC YWHAQ	7 interacting genes: BACE2 DIP2A ICOS PPP2CB SGO1 SH3GLB1 SLC27A2
Entrez ID		11001	23308
HPRD ID		11935	05757
Ensembl ID		ENSG00000140284	ENSG00000160223
Uniprot IDs		O14975	A0N0L8 B7Z1W8 O75144
PDB IDs			6X4G 6X4T
Enriched GO Terms of Interacting Partners?
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