BRD8 and CD276

		BRD8	CD276
Description		bromodomain containing 8	CD276 molecule
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Swr1 Complex Nucleoplasm Mitochondrion NuA4 Histone Acetyltransferase Complex	External Side Of Plasma Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Nuclear Receptor Coactivator Activity Thyroid Hormone Receptor Binding	Signaling Receptor Binding Protein Binding
	Biological Process	Cell Surface Receptor Signaling Pathway Histone Acetylation Regulation Of Growth Histone H4 Acetylation Histone H2A Acetylation Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Thyroid Hormone Stimulus	Regulation Of Cytokine Production Positive Regulation Of Interferon-gamma Production Positive Regulation Of T Cell Proliferation T Cell Activation Regulation Of Immune Response T Cell Receptor Signaling Pathway
Pathways		HATs acetylate histones
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Menarche (age at onset) ( 25231870)	Alanine aminotransferase levels ( 33547301 34315874) Aspartate aminotransferase levels ( 33547301 34315874) Bipolar disorder ( 31043756 21738484) Cold medicine-related Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) with severe ocular complications ( 28100913) Gamma glutamyl transferase levels ( 29403010 33339817) Liver enzyme levels (alanine transaminase) ( 33972514) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514 22001757) Tourette syndrome ( 30818990)
Interacting Genes		14 interacting genes: AGTR1 CD276 EP400 FSD2 IL3 MCRS1 MIS18A MRGBP PIN1 PPARG RXRA THRB TRRAP WEE1	5 interacting genes: ACSBG1 ACTL7B BRD8 BRDT VPS26B
Entrez ID		10902	80381
HPRD ID		04166	05756
Ensembl ID		ENSG00000112983	ENSG00000103855
Uniprot IDs		B4DEG9 B4DMS9 B4DN43 Q9H0E9	A0A0C4DGH0 A8K9J6 Q5ZPR3
PDB IDs
Enriched GO Terms of Interacting Partners?
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