NOXA1 and NOX1

Number of citations of the paper that reports this interaction (PubMedID 16329988)
7

Data Source:
BioGRID (pull down)

		NOXA1	NOX1
Description		NADPH oxidase activator 1	NADPH oxidase 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol NADPH Oxidase Complex	Early Endosome Plasma Membrane Cell Junction Cell Projection NADPH Oxidase Complex
	Molecular Function	Protein Binding Superoxide-generating NADPH Oxidase Activator Activity SH3 Domain Binding Enzyme Binding Small GTPase Binding	Voltage-gated Ion Channel Activity Protein Binding Superoxide-generating NAD(P)H Oxidase Activity Small GTPase Binding Metal Ion Binding NADP Binding
	Biological Process	Superoxide Metabolic Process Regulation Of Hydrogen Peroxide Metabolic Process Superoxide Anion Generation Regulation Of Catalytic Activity Regulation Of Respiratory Burst	Angiogenesis Regulation Of Systemic Arterial Blood Pressure By Renin-angiotensin NADP Metabolic Process Defense Response Inflammatory Response Signal Transduction Regulation Of Blood Pressure Positive Regulation Of Cell Population Proliferation Positive Regulation Of Vascular Endothelial Growth Factor Production Cell Migration Extracellular Matrix Organization Ion Transmembrane Transport Regulation Of Ion Transmembrane Transport Superoxide Anion Generation Hydrogen Peroxide Metabolic Process Positive Regulation Of Integrin Biosynthetic Process Respiratory Burst Positive Regulation Of JNK Cascade Positive Regulation Of Smooth Muscle Cell Proliferation Intracellular PH Elevation Cellular Response To Hyperoxia Oxygen Metabolic Process Positive Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Cellular Stress Response To Acidic PH
Pathways		RHO GTPases Activate NADPH Oxidases CDC42 GTPase cycle RAC1 GTPase cycle RAC3 GTPase cycle WNT5:FZD7-mediated leishmania damping	RHO GTPases Activate NADPH Oxidases CDC42 GTPase cycle RAC1 GTPase cycle RAC3 GTPase cycle WNT5:FZD7-mediated leishmania damping
Drugs			Oxygen
Diseases
GWAS		Response to fenofibrate (total cholesterol levels) ( 27002377)
Interacting Genes		57 interacting genes: ANKRD55 C19orf54 C9orf24 CACNA1A CEP70 CFP CRYBA1 CTDSP1 CYSRT1 DCLRE1B DDAH2 DUSP4 EP300 FAT1 GATAD2B IL16 KCTD15 KRTAP13-1 KRTAP15-1 KRTAP19-4 KRTAP19-7 KRTAP8-1 LASP1 LMO2 MAPK1 MAPK11 METTL27 MORN3 MYLIP NAA10 NADSYN1 NCF1 NDUFAB1 NOX1 NOXO1 PFDN5 PLA2G10 PRKACA PRKCA PRKCG QARS1 RAC1 RAC2 REL RIMBP3 RIMBP3C SMUG1 TCF19 TCF4 TGS1 TRAF2 TRIM23 UBAP2 WDR83 ZC2HC1C ZNF474 ZNF620	5 interacting genes: ARHGEF7 CYBA NOXA1 NOXO1 TBXA2R
Entrez ID		10811	27035
HPRD ID		17644	02203
Ensembl ID		ENSG00000188747	ENSG00000007952
Uniprot IDs		Q86UR1	A6NGA6 Q1ZYL4 Q9Y5S8
PDB IDs
Enriched GO Terms of Interacting Partners?
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