PTTG2 and SUOX

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PTTG2	SUOX
Description		pituitary tumor-transforming 2	sulfite oxidase
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Mitochondrion Mitochondrial Intermembrane Space Mitochondrial Matrix
	Molecular Function	Molecular_function SH3 Domain Binding	Protein Binding Sulfite Oxidase Activity Heme Binding Molybdenum Ion Binding Molybdopterin Cofactor Binding
	Biological Process	Homologous Chromosome Segregation Chromosome Organization Negative Regulation Of Mitotic Sister Chromatid Separation	Sulfur Compound Metabolic Process
Pathways			Sulfide oxidation to sulfate
Drugs			{[2-Amino-4-oxo-6,7-di(sulfanyl-ÎºS)-3,5,5a,8,9a,10-hexahydro-4H-pyrano[3,2-g]pteridin-8-yl]methyl dihydrogenato(2-) phosphate}(dioxo)sulfanylmolybdenum
Diseases
GWAS		Metabolite levels ( 23823483) Periodontal microbiota ( 22699663) Response to antidepressants (symptom remission) ( 29160301) Response to SSRI (symptom remission) ( 29160301)	Allergic disease (asthma, hay fever or eczema) ( 29083406 29785011) Anorexia nervosa ( 28494655) Asthma ( 31959851 32296059 31619474) Asthma (adult onset) ( 31036433) Asthma (childhood onset) ( 31036433) Asthma or allergic disease (pleiotropy) ( 29785011) Brain morphology (MOSTest) ( 32665545) Cognitive function ( 25644384) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Gastroesophageal reflux disease ( 31527586) Intelligence (MTAG) ( 29326435) Medication use (glucocorticoids) ( 31015401) Pediatric autoimmune diseases ( 26301688) Polycystic ovary syndrome ( 22885925) Refractive error ( 32231278) Type 1 diabetes ( 18198356 31152121) Vitiligo ( 22951725)
Interacting Genes		13 interacting genes: AGR2 APP CSNK2B EML2 PRR20A PRR20B PRR20C PRR20D PRR20E RCOR3 RIPPLY1 SLC30A9 SUOX	82 interacting genes: ACOT11 BAG4 C1D C5orf51 CAMK2A CAP1 CCDC103 CDCA4 CEP76 COA7 COPS8 CRX CTAG1A CTAG1B CYB5R2 DMAP1 DUSP21 EIF3F ERICH4 EYA2 FAM217B FMNL2 FMR1 FNDC3B GOLGA6L9 HADHB HMG20A INCA1 ING5 ISCA2 ITGB3BP KIAA0753 KRT26 KRT27 KRT34 KRT4 KRT40 LMO4 MAGEA11 MAGEB10 MBD3L1 MDFI MED28 MEIS3 MORN3 MRPS35 MYL7 MYO1B NUP62 PEX19 PIH1D2 POMC PRRX1 PTTG2 REL RELA RHOH RINT1 RNF41 RPLP1 RSKR RUSC1 SERTAD3 SGTA SH3BP5L SNF8 SOHLH1 SPC24 STAT5B STH SYNGAP1 TAS2R7 TEX12 TRIB3 TSC1 UBQLN2 UBR2 VBP1 VPS28 ZNF143 ZNF576 ZXDC
Entrez ID		10744	6821
HPRD ID		09176	06055
Ensembl ID		ENSG00000250254	ENSG00000139531
Uniprot IDs		Q9NZH5	A0A024RB79 P51687
PDB IDs			1MJ4
Enriched GO Terms of Interacting Partners?
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