SIX2 and EYA1

  • Number of citations of the paper that reports this interaction (PubMedID 28514442)
  • 406
  • Data Source:
  • BioGRID (affinity chromatography technology)
  • HPRD (in vitro, two hybrid, in vivo)

SIX2

EYA1

Description SIX homeobox 2 EYA transcriptional coactivator and phosphatase 1
Image No pdb structure No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adolescent idiopathic scoliosis ( 30395268)
  • Alanine aminotransferase levels ( 33547301 34315874)
  • Aspartate aminotransferase levels ( 33547301 34315874)
  • Bell's palsy ( 33602968)
  • Chin dimples ( 27182965)
  • Chronic obstructive pulmonary disease-related biomarkers ( 23144326)
  • Heel bone mineral density ( 30598549 28869591)
  • Hypospadias ( 25108383)
  • Longevity (85 years and older) ( 24688116)
  • Paneth cell defects in Crohn's disease ( 28352666)
  • Sleep-related phenotypes ( 17903308)
  • Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993)
  • Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
  • Waist-to-hip ratio adjusted for BMI ( 26426971)
  • Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500)
  • Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500)
  • Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
  • Waist-to-hip ratio adjusted for body mass index ( 28448500)
Interacting Genes 8 interacting genes: APP CDKN2A CLIP4 EYA1 EYA3 TLE1 TLE3 TLE5 9 interacting genes: DACH1 GNAI2 GNAZ GSK3B H2AX NDUFB9 SIX1 SIX2 SIX3
Entrez ID 10736 2138
HPRD ID 05408 03388
Ensembl ID ENSG00000170577 ENSG00000104313
Uniprot IDs Q8TBA2 Q9NPC8 A0A024R813 A0A2R8Y6K4 A6NCB9 B3KXR1 F8WB53 Q0P517 Q99502
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?