TNFSF13B and TNFRSF17

Number of citations of the paper that reports this interaction (PubMedID 10801128)
268

Data Source:
HPRD (in vivo, in vitro)

		TNFSF13B	TNFRSF17
Description		TNF superfamily member 13b	TNF receptor superfamily member 17
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytoplasm Plasma Membrane Focal Adhesion Integral Component Of Membrane Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm	Plasma Membrane Endomembrane System Integral Component Of Membrane
	Molecular Function	Signaling Receptor Binding Cytokine Activity Tumor Necrosis Factor Receptor Binding Protein Binding Receptor Ligand Activity	Protein Binding Signaling Receptor Activity
	Biological Process	B Cell Homeostasis Positive Regulation Of Germinal Center Formation Immune Response Signal Transduction B Cell Differentiation Positive Regulation Of B Cell Proliferation T Cell Costimulation B Cell Costimulation Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of T Cell Proliferation	Adaptive Immune Response Lymphocyte Homeostasis Signal Transduction Multicellular Organism Development Tumor Necrosis Factor-mediated Signaling Pathway
Pathways		TNFR2 non-canonical NF-kB pathway TNFs bind their physiological receptors TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway	TNFs bind their physiological receptors
Drugs		1,4-Dioxane Belimumab	Belantamab mafodotin
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Blood protein levels ( 30072576) HDL cholesterol levels ( 32203549) IgG levels ( 28628107) Metabolite levels ( 23823483) Monocyte count ( 32888494) Monocyte percentage of white cells ( 32888494) Myeloid white cell count ( 27863252) Non-albumin protein levels ( 29403010) Platelet count ( 32888494 27863252) Platelet distribution width ( 32888494 27863252) Plateletcrit ( 32888494 27863252) Spleen volume ( 34128465) Tonsillectomy ( 27182965 28928442) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683) White blood cell count ( 27863252)	Blood protein levels ( 30072576) Phenylephrine infusion rate during anesthesia ( 31455332) QT interval ( 19305408) Testicular germ cell tumor ( 26503584)
Interacting Genes		5 interacting genes: APP TNFRSF13B TNFRSF13C TNFRSF17 TNFSF13	9 interacting genes: ABCC1 CMTM7 PEX16 TMBIM6 TNFSF13 TNFSF13B TRAF1 TRAF2 TRAF3
Entrez ID		10673	608
HPRD ID		04914	00144
Ensembl ID		ENSG00000102524	ENSG00000048462
Uniprot IDs		A0A0U5J7Q1 Q9Y275	Q02223
PDB IDs		1JH5 1KD7 1KXG 1OQD 1OQE 1OSG 3V56 4V46 4ZCH 5Y9J 6FXN	1OQD 1XU2 2KN1 4ZFO 6J7W
Enriched GO Terms of Interacting Partners?
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