FARS2 and PPP1R16B

  • Number of citations of the paper that reports this interaction (PubMedID 32296183)
  • 86
  • Data Source:
  • BioGRID (two hybrid)

FARS2

PPP1R16B

Description phenylalanyl-tRNA synthetase 2, mitochondrial protein phosphatase 1 regulatory subunit 16B
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Change in glucose in response to thiazide diuretic treatment in hypertension ( 29523524)
  • Copper levels ( 26025379)
  • Height ( 28552196)
  • JT interval (sulfonylurea treatment interaction) ( 27958378)
  • Metabolite levels ( 23823483)
  • Obesity (early onset extreme) ( 23563609)
  • Subjective response to placebo treatment in childhood asthma (change in cough/wheeze) ( 31557306)
  • Alcohol dependence or chronic alcoholic pancreatitis or alcohol-related liver cirrhosis ( 28714907)
  • Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203)
  • Diverticular disease ( 30177863)
  • Huntington's disease progression ( 28642124)
  • Mean corpuscular volume ( 32888494)
  • Platelet distribution width ( 32888494)
  • Schizophrenia ( 25056061 29483656 30285260)
Interacting Genes 69 interacting genes: ADAMTSL4 AGTRAP AJUBA AP1B1 APPL1 BACH2 BAG4 BANP BEX5 CALCOCO2 CBY2 CCDC152 CDCA4 CMTM5 CYSRT1 DGAT2L6 DPH2 DVL3 FHL5 FKBP7 FSD2 GRB10 HIGD1C HMBOX1 HOMEZ IKZF3 ISY1-RAB43 KCNF1 KCTD17 KRT13 KRT31 KRT34 KRT40 KRTAP1-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP3-3 MAN1C1 MDFI MESD MID2 MKRN3 MORN3 NFKBID NOTCH2NLA PCSK5 PPP1R16B RCBTB2 RIMBP3C SPRY1 STX11 SYP TADA2A TEPSIN TFCP2 TPM2 TRAF2 TRIM27 TRIM54 TRIP6 YIF1A ZNF438 ZNF500 ZNF526 ZNF655 ZRANB1 45 interacting genes: ATPAF2 CDCA7L CDK5RAP1 CEP55 CEP70 CRX DVL2 DVL3 FAM83A FAM83D FARS2 FLYWCH1 GATA1 GFAP GOLGA2 HAPLN2 IKZF3 KCTD9 MAGOH MCEE MISP MYL9 NEFL NFX1 PATZ1 PHC2 PLEKHN1 PPP1CA PPP1CB RBPMS RFC5 SCNM1 SF3B4 SHC3 SSR4 TACO1 TADA2A TASOR2 TFIP11 TLE5 TTI1 TUFM TXN2 ZNF410 ZNF564
Entrez ID 10667 26051
HPRD ID 09946 15168
Ensembl ID ENSG00000145982 ENSG00000101445
Uniprot IDs O95363 Q96T49
PDB IDs 3CMQ 3HFV 3TEG 3TUP 5MGH 5MGU 5MGV 5MGW
Enriched GO Terms of Interacting Partners?
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