KHDRBS3 and SGSM2

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		KHDRBS3	SGSM2
Description		KH RNA binding domain containing, signal transduction associated 3	small G protein signaling modulator 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Protein-containing Complex	Cytoplasm Melanosome
	Molecular Function	RNA Binding MRNA Binding Protein Binding SH3 Domain Binding Protein Domain Specific Binding Identical Protein Binding	GTPase Activator Activity Small GTPase Binding
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome	Intracellular Protein Transport Late Endosome To Golgi Transport Positive Regulation Of GTPase Activity Activation Of GTPase Activity
Pathways		PTK6 Regulates Proteins Involved in RNA Processing
Drugs
Diseases
GWAS		Chronotype ( 30696823) Colorectal cancer ( 34062886) Disease progression in age-related macular degeneration ( 29346644) Polycystic ovary syndrome ( 25574032) Squamous cell lung carcinoma ( 28604730) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)	Aortic root size ( 19584346) Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (MOSTest) ( 32665545) Fasting blood proinsulin levels ( 23263489) Household income (MTAG) ( 31844048) Insulin-related traits (multivariate analysis) ( 32002517) Multiple sclerosis ( 31604244) Number of sexual partners ( 30643258) Proinsulin levels ( 21873549) Schizophrenia ( 25056061)
Interacting Genes		57 interacting genes: AQP1 BAHD1 CACNA1A CCDC187 CCDC33 CNNM3 DMRT3 DOCK2 FBXO7 FUS FXR1 HBZ HNRNPC HNRNPK INPP5D KHDRBS1 KHDRBS2 LMNTD2 LNX1 MARK4 MYPOP NCOA5 NELFB NUDT18 OGT PCDHB14 PPP1R13B PRMT1 PRPF31 PRR3 PSMA1 PSMF1 PTBP2 RASAL3 RASD1 RBBP6 RBM3 RBM7 RBMX RBMY1A1 RFC3 RPH3AL SGSM2 SIAH1 SLIT3 SNRPC SNX18 SRSF9 TSGA10IP TYK2 U2AF2 YTHDC1 ZNF326 ZNF408 ZNF575 ZNF580 ZNF688	20 interacting genes: AFP CA12 CELSR3 CHD3 EGFR FNBP1L GDPD2 ILF2 KHDRBS3 MPP1 MTDH PNO1 PTN RAB2A RAB2B RAB3A RAB3B RAB9B RGMA RPS25
Entrez ID		10656	9905
HPRD ID		10007	15284
Ensembl ID		ENSG00000131773	ENSG00000141258
Uniprot IDs		O75525	B9A6J3 O43147
PDB IDs		5EL3 5ELR 5ELS 5ELT 5EMO
Enriched GO Terms of Interacting Partners?
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