IGF2BP3 and MKRN2

Number of citations of the paper that reports this interaction (PubMedID 32560817)
0

Data Source:
BioGRID (enzymatic study)

		IGF2BP3	MKRN2
Description		insulin like growth factor 2 mRNA binding protein 3	makorin ring finger protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol
	Molecular Function	RNA Binding MRNA Binding MRNA 3'-UTR Binding Protein Binding Translation Regulator Activity MRNA 5'-UTR Binding	RNA Binding Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Regulation Of Cytokine Production Translation Nervous System Development Anatomical Structure Morphogenesis Regulation Of Gene Expression Negative Regulation Of Translation MRNA Transport Regulation Of RNA Metabolic Process	Biological_process Protein Ubiquitination
Pathways		Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA
Drugs
Diseases
GWAS		Birth weight ( 31043758 27680694) Height ( 28552196 20881960 25282103 23563607) Hip circumference adjusted for BMI ( 34021172 25673412) Infant length ( 25281659) Offspring birth weight ( 31043758) Personality dimensions ( 23903073) Tau burden ( 33426524) Type 2 diabetes ( 30297969) White blood cell count ( 32888494)	Hip index ( 34021172) Monocyte percentage of white cells ( 32888494) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		78 interacting genes: DUX4 MEOX2 MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I MKRN2 OGT PCBP1 PIH1D2	15 interacting genes: C1orf109 CLK1 EIF3F IGF2BP3 MRPS25 NDN PALS2 PDLIM2 RACK1 RBCK1 RELA UBE2D1 UBE2D4 UBE2K UBE2L3
Entrez ID		10643	23609
HPRD ID		16306	09761
Ensembl ID		ENSG00000136231	ENSG00000075975
Uniprot IDs		O00425	Q9H000
PDB IDs		2E44 6FQ1 6FQR 6GQE 6GX6
Enriched GO Terms of Interacting Partners?
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