RABAC1 and LEMD3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		RABAC1	LEMD3
Description		Rab acceptor 1	LEM domain containing 3
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus Plasma Membrane Synaptic Vesicle Membrane Integral Component Of Membrane	Nuclear Inner Membrane Integral Component Of Nuclear Inner Membrane Membrane Integral Component Of Membrane Nuclear Membrane
	Molecular Function	Protein Binding Protein C-terminus Binding Identical Protein Binding Proline-rich Region Binding	Protein Binding Chromatin DNA Binding
	Biological Process		Nuclear Envelope Organization Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of BMP Signaling Pathway Negative Regulation Of Activin Receptor Signaling Pathway Regulation Of Intracellular Signal Transduction
Pathways			Nuclear Envelope Breakdown Initiation of Nuclear Envelope (NE) Reformation Depolymerisation of the Nuclear Lamina RAC1 GTPase cycle RAC2 GTPase cycle RHOD GTPase cycle RHOG GTPase cycle RAC3 GTPase cycle RND3 GTPase cycle RND2 GTPase cycle RND1 GTPase cycle
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Left-handedness ( 32989287)	Brain morphology (MOSTest) ( 32665545) Dentate gyrus granule cell layer volume ( 30279459) Dentate gyrus molecular layer volume ( 30279459) Height ( 31562340) Hippocampal fissure volume ( 30279459) Hippocampal subfield CA1 volume ( 30279459) Hippocampal subfield CA1 volume (corrected for total hippocampal volume) ( 30279459) Hippocampal subfield CA3 volume ( 30279459) Hippocampal subfield CA4 volume ( 30279459) Subiculum volume ( 30279459) Total hippocampal volume ( 30279459) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex interaction ( 26426971)
Interacting Genes		94 interacting genes: ABHD4 C6orf47 CMTM3 COQ8A CRB3 CREB3 CYBRD1 DUSP12 EI24 EMP1 F11R FHIP1B FXR1 FXR2 GDI1 GPR152 HRAS HRG HSD17B13 LEMD3 LMNA LNX1 LTBR MAD2L1 MCF2L MIEF2 NAT14 NDRG2 NDRG4 NIF3L1 NR3C2 NTAQ1 NUDT18 PBX3 PLEKHF2 PLK1 RAB17 RAB1A RAB22A RAB33A RAB3A RAB4A RAB4B RAB5A RAB5B RAB5C RAB6A RAB7A RAP1A RASD2 REEP2 REEP5 RETREG3 RGS2 RHEB RHOA RIC8A RIMS2 RIN3 RNF5 RPS20 RRAS2 S100B SGK1 SH3GL3 SH3GLB1 SLAMF6 SNCA SNX1 SNX10 SNX11 SNX15 SNX17 SNX8 SPG21 SSR3 STIM1 STOML2 SYT16 TMEM115 TMEM14B TMEM42 TMX2 TNIP1 TRIM32 TSHR TUBB2A TXN2 UBE2I VAMP2 VIM VTA1 WIPI2 ZFYVE21	7 interacting genes: BCLAF1 RABAC1 REEP4 SMAD1 SMAD2 SMAD3 SMAD9
Entrez ID		10567	23592
HPRD ID		05375	09704
Ensembl ID		ENSG00000105404	ENSG00000174106
Uniprot IDs		Q9UI14	A0A024RBB9 Q9Y2U8
PDB IDs			2CH0 5ZOJ 5ZOK
Enriched GO Terms of Interacting Partners?
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